Asset Publisher

angle-left Laurent Legault, MD

Scientist, RI-MUHC,

Child Health and Human Development Program

Assistant Professor, Department of Pediatrics, Division of Endocrinology, Faculty of Medicine, McGill University

 

Keywords


diabetes • prevention • obesity • technology

Research Focus


My research focuses on the development of an a closed loop system (also known as artifical pancreas) for the treatment of type 1 diabetes, as well as the prevention and management of pediatric obesity and its complications, including type 2 diabetes and prevention of type 1 diabetes.

Selected Publications


  • Haidar A, Legault L, Dallaire M, Alkhateeb A, Coriati A, Messier V, Cheng P, Millette M, Boulet B, Rabasa-Lhoret R. Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial. CMAJ. 2013 Mar 5;185(4):297-305. doi: 10.1503/cmaj.121265. Epub 2013 Jan 28. PMID: 23359039.

  • Haidar A, Legault L, Messier V, Mitre TM, Leroux C, Rabasa-Lhoret R. Comparison of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional insulin pump therapy for glycaemic control in patients with type 1 diabetes: an open-label randomised controlled crossover trial. Lancet Diabetes Endocrinol. 2015 Jan;3(1):17-26. doi: 10.1016/S2213-8587(14)70226-8. Epub 2014 Nov 27. PMID: 25434967.

  • Perez A, Holt N, Gokiert R, Chanoine JP, Legault L, Morrison K, Sharma A, Ball G. Why don't families initiate treatment? A qualitative multicentre study investigating parents' reasons for declining paediatric weight management. Paediatr Child Health. 2015 May;20(4):179-84. PMID: 26038633.

  • Haidar A, Legault L, Matteau-Pelletier L, Messier V, Dallaire M, Ladouceur M, Rabasa-Lhoret R. Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial. Lancet Diabetes Endocrinol. 2015 Aug;3(8):595-604. doi: 10.1016/S2213-8587(15)00141-2. Epub 2015 Jun 8. PMID: 26066705.

  • Legault L. Is the artificial pancreas coming to a home near you? Lancet Diabetes Endocrinol. 2015 Dec;3(12):916-7. doi: 10.1016/S2213-8587(15)00369-1. Epub 2015 Sep 30. PMID: 26432774.