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angle-left Lawrence Joseph, PhD

Senior Scientist, RI-MUHC,

Infectious Diseases and Immunity in Global Health Program

Full Professor, Department of Epidemiology and Biostatistics



Bayesian biostatistics • epidemiology • diagnostic tests • research design.

Research Focus

My research focuses on Bayesian biostatistical modeling. I am currently focusing on three particular topics: diagnostic tests in the absence of a gold standard, Bayesian methods for study design and sample size determination, and biostatistical consulting and collaboration.

Selected Publications

Click on Pubmed to see my current publications list

  • Joseph L, Bélisle P. Bayesian sample size determination for case-control studies when exposure may be misclassified. American Journal of Epidemiology (Accepted)

  • Dendukuri N, Schiller I, Joseph L, Pai M. Bayesian meta-analysis of the accuracy of a test for tuberculous pleuritis in the absence of a gold-standard reference. Biometrics 2012;68(4):1285-1293

  • Ladouceur M, Rahme E, Scott A, Schwartzman K, Joseph L. Modeling continuous diagnostic test data using approximate Dirichlet process distributions. Statistics in Medicine 2011;30(21):2648-2662

  • Weichenthal S, Joseph L, Bélisle P, Dufresne A. Bayesian estimation of the probability of asbestos exposure from lung fibre counts. Biometrics 2010;66(2):603-612

  • Dendukuri N, Bélisle P, Joseph L. Bayesian sample size determination for diagnostic test studies in the absence of a gold standard: Comparing identifiable to non-identifiable models. Statistics in Medicine 2010;29(26):2688-2697