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Ronald Olivenstein, MD

Investigator, RI-MUHC, Glen site

Translational Research in Respiratory Diseases Program

Associate Professor, Department of Medicine, Division of Respiratory Medicine, Faculty of Medicine, McGill University

 

Keywords


asthma • bronchoscopy • chronic obstructive pulmonary disease (COPD) • cytokines • inflammation

Research Focus


My research focuses on asthma and chronic obstructive pulmonary disease (COPD). My research interests include clinical trials in asthma and COPD, investigations into airway inflammation in severe asthma and innovative therapies such as bronchial thermoplasty I have collaborated extensively with industry in testing the effects of novel therapeutic agents in asthma and have helped to establish a well-characterized severe asthma cohort at the Montreal Chest Institute.

Selected Publications


Click on Pubmed to see my current publications list

  • Poon AH, Chouiali F, Tse SM, Litonjua AA, Hussain SN, Baglole CJ, Eidelman DH, Olivenstein R, Martin JG, Weiss ST, Hamid Q, Laprise C. Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol. 2012 Feb;129(2):569-71. doi: 10.1016/j.jaci.2011.09.035. Epub 2011 Oct 29. PMID: 22040902.

  • Laviolette M, Gossage DL, Gauvreau G, Leigh R, Olivenstein R, Katial R, Busse WW, Wenzel S, Wu Y, Datta V, Kolbeck R, Molfino NA. Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol. 2013 Nov;132(5):1086-1096.e5. doi: 10.1016/j.jaci.2013.05.020. Epub 2013 Jul 16. PMID: 23866823.

  • Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Hales JB, McEvoy C, Slebos DJ, Holmes M, Phillips MJ, Erzurum SC, Hanania NA, Sumino K, Kraft M, Cox G, Sterman DH, Hogarth K, Kline JN, Mansur AH, Louie BE, Leeds WM, Barbers RG, Austin JH, Shargill NS, Quiring J, Armstrong B, Castro M; Asthma Intervention Research 2 Trial Study Group. Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol. 2013 Dec;132(6):1295-302. doi: 10.1016/j.jaci.2013.08.009. Epub 2013 Aug 30. PMID: 23998657.

  • Arron JR, Choy DF, Laviolette M, Kelsen SG, Hatab A, Leigh R, Thomson NC, Bleecker ER, Olivenstein R, Avila PC, Jarjour NN, Castro M, Gauvreau GM, Good JT, Kline JN, Mansur A, Mayers I, Heaney LG, Hamid Q, Harris JM. Disconnect between sputum neutrophils and other measures of airway inflammation in asthma. Eur Respir J. 2014 Feb;43(2):627-9. doi: 10.1183/09031936.00117013. Epub 2013 Oct 31. PMID: 24176993.

  • Lemière C, Tremblay C, FitzGerald M, Aaron SD, Leigh R, Boulet LP, Martin JG, Nair P, Olivenstein R, Chaboillez S. Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects. Can Respir J. 2011 Sep-Oct;18(5):278-82. PMID: 21969930.