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Cynthia Goodyer, PhD

Scientist, RI-MUHC, Glen site

Child Health and Human Development Program

Associate Professor, Department of Pediatrics, Division of Experimental Medicine, Faculty of Medicine, McGill University

 

Keywords


growth • gene regulation • obesity • cancer • endocrine disruptors

Research Focus


My research focuses on two questions: (1) How is expression of the human growth hormone receptor regulated during childhood growth, obesity and cancer; and (2) what are the possible endocrine disruptor effects of certain environmental chemical contaminants (brominated flame retardants) on the human reproductive system during development and in the adult.

Selected Publications


Click on Pubmed to see my current publications list

  • Kenth, G.*, Puzhko, S.+ and Goodyer, C.G. Human growth hormone receptor gene expression is regulated by Gfi-1/Gfi-1b and GAGA cis-elements. Mol Cell Endocrinol 335: 135-147, 2011. PMID: 21238539.

  • Erman, A.*, Wabitsch, M. and Goodyer, C.G. Human growth hormone receptor (GHR) expression in obesity: II. Regulation of the human GHR gene by obesity-related factors. Int J Obesity 35: 1520-1529, 2011. PMID: 21386799.

  • Rawn, D.F.K., Gaertner, D.W., Weber, D., Curran, I.H.A., Cooke G.M. and Goodyer, C.G. Hexabromocyclododecane concentrations in Canadian human fetal liver and placental tissues. Science of the Total Environment 468-9C: 622-629, 2014. PMID: 24061053.

  • Elzein, S.* and Goodyer, C.G. Regulation of human growth hormone receptor expression by microRNAs. Mol Endocrinol 28: 1448-1459, 2014. PMID: 25073105.

  • Poon, S., Wade, M.W., Aleksa, K., Rawn, D.F.K., Carnevale, A., Gaertner, D.W., Sadler, A., Breton, F., Koren, G., Ernest, S.R., Lalancette, C, Robaire, B., Hales, B.F. and Goodyer, C.G. Hair as a biomarker of exposure to polybrominated diphenyl ethers (PBDEs). Environ Sci Technol 48: 14650-14658, 2014. PMID: 25387207.