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Emil Nashi, MD, MSc, PhD

Research Institute of the McGill University Health Centre

Associate Member
Infection and immunity


McGill University Health Centre (MUHC)

Medical Scientist


McGill University

Department of Medicine


Research Interest


My research focuses on studying autoimmune disease, in particular lupus. We are currently focusing on B cells, which are cells that play an important role in lupus. In particular, we are currently studying how B cells respond to their environment and comparing this between lupus patients and people without autoimmune disease.

Research Foci


  • SLE
  • BCR signaling
  • genomics
  • translational research

Keywords


B cells, signaling, genetics, autoimmune disease, lupus.

Selected Publications


  • Nashi E, Rauch J, Goedert JJ, Pineau CA and Bernatsky S., CXC chemokine receptor type 4 in systemic lupus., J Autoimmun Cell Response., Volume 1, Issue 2, 1-2 (June 2014)

  • Manjarrez-Orduño N , Marasco E , Chung SA , Katz MS , Kiridly JF , Simpfendorfer KR , Freudenberg J , Ballard DH , Nashi E , Hopkins TJ , Cunninghame Graham DS , Lee AT , Coenen MJ , Franke B , Swinkels DW , Graham RR , Kimberly RP , Gaffney PM , Vyse TJ , Behrens TW , Criswell LA , Diamond B , Gregersen PK, CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation., Nature genetics, Volume 44, Issue 11 (November 2012)

  • Nashi E , Wang Y , Diamond B, The role of B cells in lupus pathogenesis., The international journal of biochemistry & cell biology, Volume 42, Issue 4 (April 2010)

  • Grimaldi C , Nashi E , Venkatesh J , Diamond B, B cell hyporesponsiveness and autoimmunity: a new paradigm., Advances in experimental medicine and biology, Volume 596 (January 2007)

  • Nashi E , Banerjee D , Crelinsten G, Hypoparathyroidism in systemic lupus erythematosus., Lupus, Volume 14, Issue 2 (January 2005)