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George Kefalas

Master of Science student
Supervisor: Dr. Louise Larose
Experimental Therapeutics and Metabolism Program

George Kefalas has been awarded scholarships from Diabète Québec, the FRQS and CIHR to study the interaction between the adaptor protein Nck1 and protein kinase PERK in the pancreatic beta cell. His project aims to test the hypothesis that preventing the Nck1/PERK interaction will improve pancreatic beta cell function and resilience to diabetes-related stress. Novel findings from this project may guide clinical care, decrease the need of multiple donors for efficient transplantation and inspire effective pharmacological strategies to prevent pancreatic beta cell failure in diabetes.