Makeda Semret, M.Sc., MD, FRCPC
hospital infections • infection control • molecular diagnostics • antimicrobial resistance
My research focuses on hospital-associated infections (HAI) in Africa and in Canada, with an emphasis on specific infection control measures that will improve quality of care and patient safety. HAI and antimicrobial resistance are a major cause of morbidity and mortality among hospitalized patients in industrialized countries. The burden of HAI and of antimicrobial resistance is largely unknown in Africa, where systematic surveillance is limited by weak laboratory infrastructure. We are systematically analyzing the characteristics of HAI in a large referral hospital in Ethiopia, in conjunction with training in infectious diseases and support of the microbiology laboratory. Additionally we are assessing the impact of laboratory diagnostics and of antimicrobial stewardship interventions on patient outcomes, antimicrobial prescriptions and antimicrobial resistance patterns in Ethiopia and in Canada.
Semret M, Law A, Turner S, de Varennes B, Ward BJ, Huynh T. A magician's tale. Can J Infect Dis Med Microbiol. 2006 Mar;17(2):133-4. No abstract available. PMID: 18418490.
Semret M, Koromihis G, MacLean JD, Libman M, Ward BJ. Mycobacterium ulcerans infection (Buruli ulcer): first reported case in a traveler. Am J Trop Med Hyg. 1999 Nov;61(5):689-93. PMID: 10586895.
Papenburg J, Karatzios C, Li Y, Bastien N, Semret M, Moore D. A near-fatal infection with oseltamivir-resistant seasonal influenza A in a previously healthy child: Case report. Can J Infect Dis Med Microbiol. 2009 Winter;20(4):e173-6. PMID: 21119797.
Semret M, Turenne CY, de Haas P, Collins DM, Behr MA. Differentiating host-associated variants of Mycobacterium avium by PCR for detection of large sequence polymorphisms. J Clin Microbiol. 2006 Mar;44(3):881-7. PMID: 16517871.
Semret M, Zhai G, Mostowy S, Cleto C, Alexander D, Cangelosi G, Cousins D, Collins DM, van Soolingen D, Behr MA. Extensive genomic polymorphism within Mycobacterium avium. J Bacteriol. 2004 Sep;186(18):6332-4. PMID: 15342607.