Marta Kaminska, B.Sc., MD, M.Sc.
sleep-disordered breathing • fatigue • cognition • neurological disorders • noninvasive ventilation
My research focuses on respiratory issues in neurological diseases, particularly sleep-related breathing disorders such as obstructive sleep apnea (OSA). It is divided in two themes. In theme 1, I study the interaction between OSA and central nervous system disorders, such as multiple sclerosis and Parkinson's disease. On the one hand, neurological disorders may lead to OSA. On the other, treating OSA may help specific symptoms and quality of life in those patients. Theme 2 relates to various aspects of respiratory care of patients with neuromuscular diseases (which cause muscle weakness). Amyotrophic lateral sclerosis (ALS) is such a disease, causing progressive weakening of respiratory muscles leading to respiratory failure. I have been studying the measurement of respiratory strength, lung volume recruitment manoeuvres (a technique that helps maintain lung health), and new modes of adjusting a ventilator for long term use at home.
Mery VP, Gros P, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea. Neurology. 2017 Mar 21;88(12):1120-1128. doi: 10.1212/WNL.0000000000003738. Epub 2017 Feb 22. PMID: 28228566.
Gros P, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Obstructive sleep apnea in Parkinson's disease patients: effect of Sinemet CR taken at bedtime. Sleep Breath. 2016 Mar;20(1):205-12. doi: 10.1007/s11325-015-1208-9. Epub 2015 Jun 13. PMID: 26070532.
Kaminska M, Browman F, Trojan DA, Genge A, Benedetti A, Petrof BJ. Feasibility of Lung Volume Recruitment in Early Neuromuscular Weakness: A Comparison Between Amyotrophic Lateral Sclerosis, Myotonic Dystrophy, and Postpolio Syndrome. PM R. 2015 Jul;7(7):677-84. doi: 10.1016/j.pmrj.2015.04.001. Epub 2015 Apr 3. PMID: 25845857.
Kaminska M, Lafontaine AL, Kimoff RJ. The Interaction between Obstructive Sleep Apnea and Parkinson's Disease: Possible Mechanisms and Implications for Cognitive Function. Parkinsons Dis. 2015;2015:849472. doi: 10.1155/2015/849472. Epub 2015 Oct 5. Review. PMID: 26509097.
Gros P, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M. Diagnosis of Obstructive Sleep Apnea in Parkinson's Disease Patients: Is Unattended Portable Monitoring a Suitable Tool? Parkinsons Dis. 2015;2015:258418. doi: 10.1155/2015/258418. Epub 2015 Oct 13. PMID: 26550519.