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Waqqas Afif, MD, M.Sc., FRCPC

Associate Investigator, RI-MUHC, Montreal General Hospital

Infectious Diseases and Immunity in Global Health Program

Assistant Professor, Department of Medicine, Division of Gastroenterology, Faculty of Medicine, McGill University

 

Keywords


inflammatory bowel disease • Crohn's disease • ulcerative colitis • biologic medications • therapeutic drug monitoring

Research Focus


My research focuses on the safety and efficiency of biologic medications in the treatment of IBD. I am interested in the use of therapeutic drug monitoring to optimize the treatment of IBD patients on biologic medications.

Selected Publications


Click on Pubmed to see my current publications list

  • Kopylov U1, Vutcovici M, Kezouh A, Seidman E, Bitton A, Afif W. Risk of Lymphoma, Colorectal and Skin Cancer in Patients with IBD Treated with Immunomodulators and Biologics: A Quebec Claims Database Study. Inflamm Bowel Dis. 2015 Aug;21(8):1847-53. doi: 10.1097/MIB.0000000000000457. PMID: 25993693.

  • Bressler B1, Marshall JK2, Bernstein CN3, Bitton A4, Jones J5, Leontiadis GI2, Panaccione R6, Steinhart AH7, Tse F2, Feagan B8; Toronto Ulcerative Colitis Consensus Group. Clinical practice guidelines for the medical management of nonhospitalized ulcerative colitis: the Toronto consensus. Gastroenterology. 2015 May;148(5):1035-1058.e3. doi: 10.1053/j.gastro.2015.03.001. Epub 2015 Mar 4. PMID: 25747596.

  • Risk of infections with biological agents. Kopylov U, Afif W. Gastroenterol Clin North Am. 2014 Sep;43(3):509-24. doi: 10.1016/j.gtc.2014.05.001. Epub 2014 Jun 16. PMID: 25110256.

  • Risk factors for lymphoma in patients with inflammatory bowel disease: a case-control study., Afif W1, Sandborn WJ, Faubion WA, Rahman M, Harmsen SW, Zinsmeister AR, Loftus EV Jr., Inflamm Bowel Dis. 2013 Jun;19(7):1384-9. doi: 10.1097/MIB.0b013e318281325e. PMID: 23535248.

  • Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease., Afif W1, Loftus EV Jr, Faubion WA, Kane SV, Bruining DH, Hanson KA, Sandborn WJ., Am J Gastroenterol. 2010 May;105(5):1133-9. doi: 10.1038/ajg.2010.9. Epub 2010 Feb 9. PMID: 20145610.