Breadcrumb

null Adel Schwertani, PhD

Senior Scientist, RI-MUHC, Glen site

Cardiovascular Health Across the Lifespan Program

Centre for Translational Biology

Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

Department of Medicine, Division of Cardiology, MUHC

 

Keywords

cardiology • heart • vasoactive substances • atherosclerosis • pulmonary hypertension

Research Focus

My research focuses on the role of vasoactive and structural protein in the pathogenesis of atherosclerosis, myocardial infarction, aortic valve disease and pulmonary hypertension. Along with my collaborators, we are also examining the role of stem cells in cardiac regeneration and personalized drug testing. We recently identified a new mediator in the pathogenesis of thrombosis and are currently working with our national and international collaborators on identifying a new therapeutic approach to pulmonary emboli and deep vein thrombosis.

Selected Publications

Click on Pubmed to see my current publications list

  • Chammas J, Delaney D, Chabaytah N, Abdulkarim S, Schwertani A. COVID-19 and the cardiovascular system: insights into effects and treatments. Can J Physiol Pharmacol. 2021 Nov;99(11):1119-1127. doi: 10.1139/cjpp-2021-0093. Epub 2021 Sep 21. PMID: 34546123.

  • Khan K, Gasbarrino K, Mahmoud I, Dufresne L, Daskalopoulou SS, Schwertani A, Cecere R. Bioactive Scaffolds in Stem Cell-Based Therapies for Myocardial Infarction: a Systematic Review and Meta-Analysis of Preclinical Trials. Stem Cell Rev Rep. 2021 Aug 31. doi: 10.1007/s12015-021-10186-y. Epub ahead of print. PMID: 34463903.

  • Khan K, Yu B, Kiwan C, Shalal Y, Filimon S, Cipro M, Shum-Tim D, Cecere R, Schwertani A. The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis. Front Cell Dev Biol. 2020 Sep 10;8:862. doi: 10.3389/fcell.2020.00862. PMID: 33015048.

  • Khan K, Albanese I, Yu B, Shalal Y, Al-Kindi H, Alaws H, Tardif JC, Gourgas O, Cerutti M, Schwertani A. Urotensin II, urotensin-related peptide, and their receptor in aortic valve stenosis. J Thorac Cardiovasc Surg. 2019 Sep 26:S0022-5223(19)32013-6. doi: 10.1016/j.jtcvs.2019.09.029. Epub ahead of print. PMID: 31679703.

  • Lee A, Wei S, Schwertani A. A Notch more: Molecular players in bicuspid aortic valve disease. J Mol Cell Cardiol. 2019 Sep;134:62-68. doi: 10.1016/j.yjmcc.2019.05.018. Epub 2019 May 28. PMID: 31150732.