Centre for Translational Biology (CTB)

The Centre for Translational Biology (CTB) is one of the three RI-MUHC research centres, which unite RI-MUHC researchers from eight interdisciplinary research programs.

CTB researchers are engaged in fundamental biomedical research, using a wide range of models and interdisciplinary approaches to understand the many factors contributing to human health. The CTB includes more than 150 RI-MUHC scientists and their teams, located at the Glen site and Montreal General Hospital (MGH) site of the McGill University Health Centre (MUHC).

The CTB houses nine core facilities or technology platforms, whose mission is to provide internal and external users access to state-of-the-art technologies and instrumentation, top-level scientific expertise, and the training necessary to promote cutting-edge research.

CTB Researchers

Profiles of CTB researchers may be accessed via their affiliated Research Program:

CTB News and Events

We are proud to celebrate the scientific achievements of our researchers and trainees in publications, grant competitions, honors and awards, and appointments, as well as in the mainstream press.

News

The Centre for Translational Biology (CTB) organizes and supports numerous speakers, seminars, and symposia throughout the year.

Events

CTB Technology Platforms

The CTB houses nine core facilities or technology platforms, whose mission is to provide internal and external users access to state-of-the-art technologies and instrumentation, top-level scientific expertise, and the training necessary to promote cutting-edge research.

The Biobank Platform fosters ethical studies of human tissues by providing expert regulatory support, sample collection and secure storage.

The Bioinformatics Platform accelerates genomics research and its applications in clinical practice, combining expertise in bioinformatics, human genetics, next-generation sequencing and molecular diagnosis.

The Containment Level 3 (CL3) Platform is a state-of-the-art biosafety facility combining the latest instrumentation for cell sorting and DNA sequencing for research on live pathogenic bacteria and viruses.

The Histopathology Platform features high-throughput, multiplex detection procedures to visualize complex biological structures and molecular components within soft tissues and bones.

The Immunophenotyping Platform is equipped with high-speed, multicolour flow cytometers and cell sorters that count and sort cells for detailed research and precision phenotyping.

The Molecular Imaging Platform offers superb technologies for high-resolution and super-resolution microscopy, providing still images and real-time movies of events as they occur within living tissues and organisms.

The Proteomics and Molecular Analysis Platform provides identification and quantification of proteins and other biomolecules using advanced mass spectrometry methods and discovery of novel drug candidates through integrated bioanalytical services.

The Small Animal Imaging Labs (SAIL) Platform is a unique and comprehensive technology suite for non-invasive imaging (MRI, PET, CT, SPECT) in pre-clinical animal models.

RI-MUHC members also benefit from the Brain Imaging Centre (BIC) at the Montreal Neurological Institute (MNI) which facilitates the development of new techniques for imaging of humans and animals. The BIC’s facilities include some of the most advanced magnetic resonance (MR), positron emission tomography (PET), and magnetoencephalography (MEG) imaging devices available.

Additionally, the RI-MUHC supports animal facilities equipped with state-of-the art imaging facilities at the Glen, MGH and MNI.

At the MNI, the Healthy Brains for Healthy Lives program (HBHL) supports the operations and expansion of core facilities and technology development platforms.