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Funding results
- CIHR CLINICAL TRIALS PROJECTS – SECOND ROUND (2024)
- SPRING 2024 CIHR COMPETITION RESULTS
- CANADA RESEARCH CHAIRS, SPRING 2024
- FRQS SALARY AWARD COMPETITION 2024-2025
- FALL 2023 CIHR COMPETITION RESULTS
- CANADA RESEARCH CHAIRS, SPRING 2023
- SPRING 2023 CIHR COMPETITION RESULTS
- FALL 2022 CIHR COMPETITION RESULTS
- CANADA RESEARCH CHAIRS, SPRING 2022
- FRQS SALARY AWARD COMPETITION 2022-2023
- FALL 2021 CIHR COMPETITION RESULTS
- CANADA RESEARCH CHAIRS, 2021 COMPETITIONS
- FRQS SALARY AWARD COMPETITION 2021-2022
- FALL 2020 CIHR COMPETITION RESULTS
- CANADA RESEARCH CHAIRS, 2020 COMPETITIONS
- FALL 2019 CIHR COMPETITION RESULTS
CIHR CLINICAL TRIALS PROJECTS – SECOND ROUND (2024)
On August 13, the Honourable Mark Holland, Minister of Health, announced that the Government of Canada is investing more than $43 million to support 14 new clinical trials focused on preparing Canada to respond to future health emergencies and advancing the country’s life sciences sector.
Researchers at the RI-MUHC will lead four of the fourteen newly funded clinical trials.
- Patrick Lawler, MD: CLEAR-HORIZONS Post-Sepsis Platform Trial: Statin Pilot RCT
- Dick Menzies, MD: Finding the right balance: An adaptive trial to identify the safest regimen with the shortest duration for TB prevention (treatment of TB Infection)
- Ruth Sapir-Pichhadze, MD, PhD: Efficacy and safety of COVID-19 vaccine Co-administration and Interval in Immunocompromised hosts (CO2I2 Trial)
- Makeda Semret: Biomarker-signature Supported Antibiotic Treatment Decisions in ICU (BAST-ICU)
The full list of funded clinical trials can be found here: CIHR Clinical Trials Projects. These trials are being supported by the Canadian Institutes of Health Research (CIHR) Clinical Trials Fund, an important part of Canada’s Biomanufacturing and Life Sciences Strategy, and Canada’s Strategy for Patient-Oriented Research.
—Published August 15, 2024
SPRING 2024 CIHR COMPETITION RESULTS
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will embark on 18 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Spring 2024 Project Grants Competition. The RI-MUHC teams received $17.3 million in project funding.
Across Canada, this competition approved 373 research grants for a total investment of approximately $325 million. In addition, 68 priority announcement grants were funded for a total amount of over $7.6 million and 5 supplemental prizes were awarded for a total of $210K.
The CIHR Project Grant program is designed to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.
”We take great pride in the accomplishments of the RI-MUHC grant recipients and their teams. Their innovative projects, supported through this competition, promise to significantly enhance Canadian healthcare across various critical domains," said Dr. Rhian Touyz, Executive Director and Chief Scientific Officer at RI-MUHC. "A number of our colleagues had the highest ranking in the peer review committees. These outcomes underscore the unwavering commitment and exceptional calibre of the RI‑MUHC research community."
Congratulations to RI-MUHC grant recipients and their teams!
PROJECT GRANTS
- Faiz Ahmad Khan, Natasha I MacDonald, and Glenda Sandy
Utirtisiniq Puvallutulirinirmut arqutigitsugu Inuit Qaujimajatuqangit: Nuisivalialuni Nunavimmiut arqirutisaginnik puvalluniup ammalu namasiangitunut anniasiuriujut Nunavimmi Decolonizing TB Healthcare Through Inuit Qaujimajatuqangit: developing Nunavimmiut-led solutions to the continuing crises of TB and inadequate healthcare in Nunavik
This grant ranked second in the “Indigenous Health Research” panel. - Andrea Benedetti and Brett D Thombs
Recovering from the COVID-19 Pandemic, Informing Future Public Health Crises, and Building a Global Evidence Base for Mental Health Research: A Systematic Review of COVID-19-related Mental Health - Sasha R. Bernatsky, Juan A. Avina-Zubieta, Hong Chen, and Audry Smargiassi
Environmental factors and risk of autoimmune rheumatic disease incidence and serology - Charles W. Bourque
Mechanisms by which MDMA (Ecstasy) can cause life-threatening hyponatremia and why females are at greater risk
This grant ranked first in the Systems & Circuits Neurosciences – A panel. - Jonathon Campbell, James C. Johnston
Risk Assessment and Determinants of Tuberculosis Associated Respiratory Impairment and Disability (RADAR-TB): A Systematic Review and Individual Participant Data Meta-Analysis - Yen-I Chen; Jeffrey Stewart T Barkun; Natalia S Causada Calo
Prophylactic EUS-guided gastroenterostomy in advanced periampullary cancers: A multicenter randomized controlled trial (INTERCEPT study)
This grant ranked first in the Clinical Investigation - C: Digestive, Endocrine and Excretory Systems panel. - Nada Jabado
Targeting vulnerabilities in oncohistone-mediated gliomas - Nada Jabado
Unraveling how de novo germline H3.3 mutations promote neurodegeneration and disease
This grant ranked third in the Cell Biology - Disease panel - Jacqueline Joza; Vidal Essebag; Jeff S Healey; Atul Verma
LEFT HF: LEFT Bundle Pacing vs Standard Right Ventricular Pacing for Heart Failure - Nadine Kronfli; Frederick L Altice
Enhancing uptake of needle and syringe programs in Canadian federal prisons - Todd C Lee; Matthew P Cheng; Nick Daneman; Joshua Davis; Anna L Goodman; Patrick R Lawler; Emily G McDonald; Dominik Mertz; Mical Paul; Deborah M Siegal; Steven Tong; Genevieve Walls
Clopidogrel vs. Aspirin in S. aureus Bacteremia (Clopido-SNAP) - Mazer, Bruce D
B-Lymphocyte derived extracellular vesicles as key regulators of allergic airway inflammation - Emily G McDonald; Matthew P Cheng; Nick Daneman; Joshua Davis; Anna L Goodman; Alexander Lawandi; Patrick R Lawler; Todd C Lee; Dominik Mertz; Mical Paul; Deborah M Siegal; Steven Tong; Genevieve Walls
Dabigatran for the adjunctive treatment of Staphylococcus aureus bacteremia: the DABI-SNAP nested randomized controlled trial
This grant ranked first in the Randomized Controlled Trials 2 panel. - Nagano, Makoto
Transient disruption of the blood-testis barrier using synthetic anti-claudin compounds in human and pig models: towards improving the efficiency of spermatogonial stem cell transplantation for fertility restoration in pediatric cancer survivors
This grant ranked third in the Clinical Investigation - A: Reproduction, Maternal, Child and Youth Health 2 panel - Jesse Papenburg; Asha C Bowen; Matthew P Cheng; Todd C Lee
Staphylococcus aureus Network Adaptive Platform trial in Pediatrics and Youth (SNAP-PY), Canada
This grant ranked third in the Randomized Controlled Trials 2 panel - Jean-Pierre Routy
ACBP as a target for immunometabolic reprogramming in people living with HIV
This grant ranked third Virology & Viral Pathogenesis panel - Jeremy Van Raamsdonk
Role of pathways of cellular resilience in longevity and neuroprotection
This grant ranked first in the Biological and Clinical Aspects of Aging panel. - Atul Verma; Jason G Andrade; Laurent Macle; Pablo Nery
Strategies for catheter ablation of persistent atrial fibrillation: a randomized comparative study (STAR AF 3)
PRIORITY ANNOUNCEMENTS
Pandemic Preparedness and Health Emergencies Research
- Maziar Divangahi
Programming Innate Memory Responses to promote host defense against SARS-CoV-2 Pneumonia
Health and Official Languages in Minority Communities
- Amal Idrissi Janati; Richard B Hovey
Utilization of Psychosocial Oncology Services by Oral Cancer Patients in Montreal Area According to Their Minority Language Profile
Racism & Racial Inequities in Sex & Gender Health Res (Bridge Funding)
- Dan Poenaru; Susan A Bartels
The impact of gender on pediatric surgical care in Africa
Learn more on the Canadian Institutes of Health Research website.
—Published August 1, 2024
CANADA RESEARCH CHAIRS, SPRING 2024
Tier 2 Canada Research Chairs are awarded to exceptional emerging researchers, acknowledged by their peers as having the potential to lead in their field. Congratulations to three RI-MUHC researchers who earned Tier 2 Chairs in spring 2024! (Competition cycle: 2023-1.)
- Sylvie Lambert, RN, PhD
Associate investigator, Cancer Research Program, RI-MUHC.
Canada Research Chair in Illness Self-Management Support Interventions for Patients and their Family Caregivers, CIHR, Tier 2 (Renewal). - Marc Martel, PhD
Scientist, Surgical and Interventional Sciences Program, RI-MUHC
Canada Research Chair in Chronic Pain, Mental Health, and Opioid Use, CIHR, Tier 2 (Renewal) - Mathieu Roy, PhD
Investigator, Brain Repair and Integrative Neuroscience Program, RI-MUHC
Canada Research Chair in Brain Imaging of Experimental and Chronic Pain, CIHR, Tier 2 (Renewal)
The Canada Research Chairs Program stands at the centre of a national strategy to make Canada one of the world's top countries in research and development. It invests approximately $311 million per year to attract and retain a diverse cadre of world-class researchers, to reinforce academic research and training excellence in Canadian postsecondary institutions.
Learn more about the competition results for McGill University
—Published July 29, 2024
FRQS SALARY AWARD COMPETITION 2024-2025
Congratulations to researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) who received salary awards from the Fonds de recherche du Québec – Santé (FRQS)!
Distinguished research scholars
- Geneviève Bernard
Leucodystrophies: un programme de recherche translationnelle - Ariane Marelli
Santé de précision pour les maladies cardiaques congénitales tout au long de la vie - George Thanassoulis
La génétique cardiovasculaire pour une prévention cardiovasculaire personalisée IV
Research scholar, Senior
- Andrea Benedetti
Défis statistiques concernant les méta-analyses des données agrégées et des données individuelles des participants
Research scholar, Junior 2
- Swneke Bailey
Découvrir les médiateurs moléculaires de la progression du cancer gastro-oesophagien et de la résistance aux médicaments
Research scholars, Junior 1
- Talia Malagon
Modèles de décision en santé et jumelage des données pour la prévention du cancer, le dépistage de cancers multiples et évaluer la résilience des soins en cancérologie
Clinical research scholars, Senior
- Patricia Li
Promouvoir l'équité en santé chez les enfants en partenariat avec les parents et les jeunes - Sushmita Pamidi
L'apnée du sommeil chez la mère pendant la grossesse et son impact sur la santé cardiométabolique de l'enfant et de la mère - François Tournoux
Technologies innovantes pour transformer la prise en charge de l'insuffisance cardiaque, l'accès aux soins et l'expérience patient - Cédric Yansouni
Catalyser le diagnostic des maladies infectieuses dans le Grand Nord du Québec ainsi qu'en milieux à faibles ressources
Clinical research scholars, Junior 2
- Deborah Assayag
Evaluer et optimiser le traitement et le pronostic en maladies pulmonaires interstitielles - Marc Beltempo
Transformation des services de soins intensifs néonataux pour améliorer les issues de santé - Yen-I Chen
Programme de développement et d'évaluation des technologies en endoscopie interventionnelle pour la prise en charge des cancers du pancréas et des voies biliaires - Heather Gill
VASCUFIT: préhabilitation pour les maladies vasculaires - une quête vers la santé et le bien-être - Catherine Goudie
Les syndromes de prédisposition génétique au cancer chez l'enfant et l'adolescent: un programme de recherche axé sur les approches de détection et d'intervention
Clinical research scholars, Junior 1
- Amine Benmassaoud
Développement de nouvelles stratégies pour améliorer la santé des patients atteints d'hypertension portale - Ana Gomez-Carrillo
Intégrer les systèmes complexes à la clinique en psychiatrie: Développer des outils d'évaluation et d'intervention centrés sur le patient - Natalia Gorelik
Optimisation de l'utilisation de l'imagerie oncologique musculo-squelettique - Jacqueline Joza
La place des nouvelles technologies dans le traitement des troubles des rythmes cardiaques : prévention des arythmies récurrentes et de l'insuffisance cardiaque - Elena Netchiporouk
Élucider les déclencheurs environnementaux et les déterminants de santé des maladies cutanées à médiation immunitaire - Romina Pace
Travailler côte à côte : Améliorer les soins et les résultatsde santé avec les peuples autochtones - Basile Tessier Cloutier
Une approche multiomique profonde pour resoudre des obstacles cliniques chez les patients atteint du cancer de l'uterus
—Published May 21, 2024
FALL 2023 CIHR COMPETITION RESULTS
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will embark on 21 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Fall 2023 Project Grants Competition. The RI-MUHC teams received over $13.65 million in project funding.
Across Canada, the competition has approved 374 research grants plus six bridge grants for a total investment of approximately $325 million. In addition, 150 priority announcement grants were funded for a total amount of over $16.42 million and 14 supplemental prizes were awarded for a total of $450K.
Congratulations to RI-MUHC grant recipients and their teams!
PROJECT GRANTS
- Carolyn Baglole
Decoding how the aryl hydrocarbon receptor (AhR) controls cigarette smoke-induced lung inflammation and development of chronic obstructive pulmonary disease (COPD) - Yen-I Chen, Nauzer Forbes
A novel through-the-scope exchangeable double balloon catheter to guide endoscopic bypass: a practice-changing technology in the management of malignant gastric outlet obstruction - Nathalie Lamarche-Vane
Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development - Monzur Murshed
Understanding how a novel mutation in matrix Gla protein causes skeletal anomalies - Cristian O'Flaherty
Sperm capacitation: A brand new perspective to tackle idiopathic male infertility - Madhukar Pai
Empowering informal healthcare providers to detect tuberculosis using tongue swabs: a field-based, open-label, cluster randomized trial in India - Ciriaco A. Piccirillo
Modelling of human FOXP3+ regulatory T cell functional development in health and disease using artificial thymic organoids. - Christian E. Rocheleau
Understanding polarized EGFR trafficking and signal regulation by RAB-10/8 and AP-1 - Shaifali Sandal
A health systems approach to improve the care of kidney transplant recipients with graft failure - Per Jesper Sjöström
Unconventional NMDAR Signalling - Per Jesper Sjöström
Neocortical Circuits in Health and Disease - Tomoko Takano, Ciriaco A. Piccirillo
Pathogenesis of idiopathic nephrotic syndrome: defining the role of B cells and autoantibodies reactive to podocyte proteins - George Thanassoulis
Genomics of Aortic Stenosis - An International Collaboration - Rhian M. Touyz
Vascular redox signaling and Nox5 define the vasculome in hypertension - Jacquetta M. Trasler
Detecting and preventing epigenetic defects and adverse health outcomes associated with assisted reproduction
PRIORITY ANNOUNCEMENTS
Pandemic Preparedness and Health Emergencies
- Andrea Benedetti, Brett D. Thombs
Recovering from the COVID-19 Pandemic, Informing Future Public Health Crises, and Building a Global Evidence Base for Mental Health Research: A Systematic Review of COVID-19-related Mental Health
Project Grant - Priority Announcement: Health and Climate Change
- Sasha R. Bernatsky, Hong Chen, Audrey Smargiassi, Juan A. Avina-Zubieta
Environmental factors and risk of autoimmune rheumatic disease incidence and serology
Sex and Gender in Health Research (Bridge funding)
- Stella S. Daskalopoulou
Identifying the Role of Sex Hormones in Carotid Atherosclerotic Plaque Instability
Research in human development, child and/or youth health in Indigenous populations
- Patricia T. Li, Ryan Giroux, Matthew Carwana, Gita Wahi, Tania Principi, Samina Ali, Ananya T. Banerjee, Evelyn Constantin, Ugochinyere Viv Ukah, Brett S. Burstein, Suzette R. Cooke, Gabrielle Freire, Christina I. Maratta, Jessica L. Foulds, Olivier Drouin, Nathalie Orr-Gaucher, April Kam, Shazeen Suleman
Race, Ethnicity, Indigenous identity and Language preference for Pediatric research in the hospital setting (REIaL-P)
HIV/AIDS and STBBI
- Nitika Pai, Qihuang Zhang, Samira Abbasgholizadeh Rahimi, Nora Engel, Suma Nair, Susan J. Bartlett
Feasibility of AnkaSmart!: a wearable-based innovation to improve sexual and reproductive health of young adult populations in India
Aging
- Jeremy Van Raamsdonk
Role of biological resilience pathways in longevity and neuroprotection
Learn more on the Canadian Institutes of Health Research website
—Published February 16, 2024
CANADA RESEARCH CHAIRS, SPRING 2023
Tier 1 Canada Research Chairs are awarded to outstanding researchers acknowledged by their peers as world leaders in their fields. Congratulations to Dr. Rhian Touyz, who earned the Tier 1 Canada Research Chair in Cardiovascular Medicine in the spring 2023 competition!
Dr. Touyz is the Executive Director and Chief Scientific Officer of the Research Institute of the McGill University Health Centre and a senior scientist in the Cardiovascular Health Across the Lifespan Program. She holds the Dr. Phil Gold Chair in Medicine and Professor in Family Medicine at McGill University.
The Canada Research Chairs Program stands at the centre of a national strategy to make Canada one of the world's top countries in research and development. It invests approximately $311 million per year to attract and retain a diverse cadre of world-class researchers, to reinforce academic research and training excellence in Canadian postsecondary institutions.
Learn more about the competition results for McGill University in the McGill Reporter
—Published August 31, 2023
SPRING 2023 CIHR COMPETITION RESULTS
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will lead 15 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Spring 2023 Project Grants Competition. The RI-MUHC teams received over $16.5 million in project funding.
Across Canada, the competition has approved 381 research grants for a total investment of approximately $325 million. In addition, 62 priority announcement grants were approved for a total of $7.2 million, along with 12 bridge grants totalling $1.2 million and five supplemental prizes totalling $250,000.
Congratulations to RI-MUHC grant recipients and their teams!
PROJECT GRANTS
- Geneviève Bernard
RNA polymerase III-related leukodystrophy: Understanding disease pathogenesis and developing novel therapeutic approaches using murine models - Julia Burnier
Modelling cancer cell-derived extracellular vesicles using synthetic nanoparticles - Jonathon Campbell, James C. Johnston, Sarah K. Brode
A Key Step to Eliminating Tuberculosis in Canada: Informing the Implementation and Scale-up of Tuberculosis Preventive Treatment - Julio F. Fiore Jr., Justin Rivard, May Lynn Quan, Jad Abou Khalil, Christine Desbiens, Emily G. McDonald, Liane S. Feldman, Ipshita Prakash, Stephanie M. Wong, Sarkis H. Meterissian, Allison Maciver, Lisa Findlay-Shirras
Comparative effectiveness of opioid versus opioid-free post-discharge analgesia after outpatient breast surgery: A randomized controlled trial - Catherine Goudie
Leveraging precision medicine and eHealth to predict cancer predisposition syndromes in children: A Canadian initiative to redress global health disparities in cancer genetics - Ariane Marelli
Exposure to Low Dose Ionizing Radiation In Adult Patients with Congenital Heart Disease - A Time Series Analysis Assessing the Past and Projecting the Future - James G. Martin
Understanding the Mechanistic Basis of Irritant-Induced Airway Dysfunction - Thomas Mavrakanas, William Beaubien-Souligny
Identification, description, and prognostic significance of latent classes based on hemodynamic indicators for patients on maintenance hemodialysis. - Suzanne N. Morin, William D.Leslie, Lisa M. Lix
Effectiveness and Safety of Long-term Antiresorptive Treatment for Osteoporosis in Canada: Improving Shared Decision Making - Dan Poenaru, Ariane Marelli
A voice to the voiceless: Longitudinal patient-reported outcomes, experiences, social determinants of health and health services utilization after major neonatal surgery - Alain Ptito
Imaging biomarkers for early identification of mTBI patients at risk for persistent post-concussive symptoms. - Shafaat A. Rabbani
Role of methyl-CpG-binding domain protein 2 (Mbd2) in breast cancer development, progression and metastasis - Jonathan D. Spicer
Role of the circadian rhythm in the regulation of the tumor microenvironment of non-small cell cancer - Donald J. van Meyel
Dual-function glutamate transporter/chloride channels in brain physiology and neurological diseases.
PRIORITY ANNOUNCEMENTS
HIV/AIDS and STBBI
- Nadine Kronfli, Frederick L. Altice
Enhancing uptake of needle and syringe programs in Canadian federal prisons
Learn more on the Canadian Institutes of Health Research (CIHR) website
—Published August 25, 2023
FALL 2022 CIHR COMPETITION RESULTS
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will embark on 31 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Fall 2022 Project Grants Competition. The RI-MUHC teams received over $16.5 million in project funding.
Across Canada, the competition has approved 382 research grants plus one bridge grant for a total investment of approximately $325 million. In addition, 190 priority announcement grants were funded for a total amount of over $22 million and 12 supplemental prizes were awarded for a total of $375K.
The CIHR Project Grant program is designed to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.
“We are extremely proud that RI-MUHC grant recipients and their teams have achieved a 24% success rate this year for CIHR project grants, which is higher than the national level,” says Dr. Rhian Touyz, Executive Director and Chief Scientific Officer, RI‑MUHC. “With the inclusion of priority announcements and bridge grants, we can celebrate the success of 43% of our submissions. This rate testifies to the deep engagement and excellence of the RI-MUHC research community.”
Congratulations to RI-MUHC grant recipients and their teams!
PROJECT GRANTS
- Suhad Ali
Pharmacological Targeting of Adenosine-to-Inosine (A-to-I) RNA Editing in Aggressive Breast Cancer Subtypes - Marcel A. Behr
Differential virulence within the Mycobacterium tuberculosis complex - Nancy E. Braverman, Robert K. Koenekoop, Catherine Argyriou
Enabling commercialization of retinal gene therapy for Zellweger Spectrum Disorder - Deborah M. Da Costa, Steven A. Grover, Elham Rahme, Ilka Lowensteyn, Jane McCusker, Nicole L. Letourneau
Evaluating Acceptability and Feasibility of an Enhanced Digital Intervention for Preventing Postpartum Mental Health Difficulties in Fathers - Deborah M. Da Costa, Elham Rahme, Mary A. De Vera, Evelyne Vinet, Paul R. Fortin
Mental Health in Individuals with Autoimmune Rheumatic Diseases During the Transition to Parenthood: A Mixed Methods Study to Identify Associated Factors and Support Needs - Roy W. Dudley, Myriam Srour, Alain Bouthillier, Alexander G. Weil, Frederic Leblond, Paule Lessard Bonaventure, Maxime Richer, Louis Crevier
Development of intraoperative label-free Raman Spectroscopy techniques to delineate Focal Cortical Dysplasia borders in Epilepsy surgery and detect cells carrying somatic variants - Alex Gregorieff, Sampath K. Loganathan, Danuta Radzioch
Defining the role of fetal reprogramming in the gut epithelium in health and disease. - Marina B. Klein, Lisa Barrett, Brian Conway, Curtis L. Cooper, Pierre Cote, Tammy L. Bourque, John J. Cox, Sahar Z. Saeed, Giada Sebastiani, Michael J. Gill, Shariq Haider, Mark W. Hull, Erica E. Moodie, Valérie Martel-Laferrière, Carrie Martin, Dimitra Panagiotoglou, Neora Pick, Marie-Louise C.Vachon, Sharon L. Walmsley, Alexander C. Wong, James R. Young
After the Cure: Measuring the full impacts of direct-acting antivirals for people living with HIV/hepatitis C virus coinfection in Canada - Richard Kremer, Ioannis Ragoussis, Catalin Mihalcioiu
Co-targeting parathyroid hormone-related protein (PTHrP) and osteoclast activation to counter breast cancer metastasis to bone. - Richard Kremer, Catalin Mihalcioiu
Anti-parathyroid hormone-related protein (PTHrP) monoclonal antibodies against metastatic cancer - Bertrand Lebouché, Kim Engler, Marie-Pascale A. Pomey,Tibor Schuster, Marina B. Klein,Tarek Hijal, David Lessard, John J. Cox, Alexandra de Pokomandy, Nadine Kronfli, Sergio Vicente, Jean-Pierre Routy, Cecilia T. Costiniuk
Implementation of a patient portal and tailored patient-reported outcome measures to improve health problem detection and retention in HIV care: The DRHIVe Study - Jean-Jacques Lebrun, Suhad Ali, Bertrand J. Jean-Claude
Exploiting a novel dual-specificity cell cycle inhibitor, KP108 as a therapeutic approach for metastatic breast cancer - James G. Martin, Maziar Divangahi
Determinants of susceptibility to influenza infection in pregnant mice Understanding the Mechanistic Basis of Irritant (Chlorine)-Induced Asthma - Sushmita Pamidi, Deborah M. Da Costa, Kaberi Dasgupta, Styliani (Stella) Daskalopoulou, Genevieve D. Eastabrook, Nelly Huynh, Richard J. Kimoff, Marie Letourneau, Barbra De Vrijer, Anne-Maude Morency
Understanding Barriers and Facilitators to the Treatment of Sleep-Disordered Breathing in Pregnancy and Postpartum - Yong Rao
Transsynaptic control of axonal transport in presynaptic assembly and function - Erwin A Schurr
Epigenetic factors affecting the anti-mycobacterial immune response of people living with HIV - Benjamin M. Smith, Mohsen Sadatsafavi, Miranda A.Kirby, Andrea Benedetti, Kate M. Johnson, Nicole Ezer
Improving Canadian Lung Cancer Screening Efficiency with a Computed Tomography Risk Classifier - Myriam Srour, Ioannis Ragoussis
Understanding the genetic architecture and pathophysiology of focal cortical dysplasias using single nucleus RNA sequencing
PRIORITY ANNOUNCEMENTS
Human Development Child and Youth Health - Mid Career Support
- Geneviève Bernard, David A. Rudko, Guangping Gao
RNA polymerase III-related leukodystrophy: Understanding disease pathogenesis and developing novel therapeutic approaches using murine models
Institute of Musculoskeletal Health and Arthritis: IMHA Mandate Areas
- Isabelle Gagnon, Laurie Plotnick, Thierry Pauyo, Ilana Greenstone, Debbie Friedman, Melissa Turner, Ramanakumar Agnihotram, Luc J. Hébert
Direct access physiotherapy in the Pediatric Emergency Department to improve access to quality care for children and adolescents with musculoskeletal injuries: a randomized control trial
Pediatric Cancer Research
- Livia Garzia, Nada Jabado
Epigenetic mechanisms of osteosarcoma pathogenesis and progression.
HIV/AIDS and STBBI
- Nadine Kronfli, Frederick L. Altice, Mark Stoove, Andrew Lloyd, Lise Lafferty, Behzad Hajarizadeh, Asim Masood
Enhancing uptake of needle and syringe programs in Canadian federal prisons - Nitika Pant Pai, Jorge Luis Martinez, Réjean Thomas, Sahir Bhatnagar
iSampleSmart!, an innovative, App-facilitated self-sampling screen and treat strategy for common bacterial STIs (Chlamydia trachomatis and Neisseria gonorrhoeae) for Canadian key populations
Epigenetics/epigenomics in human health or disease
- Shafaat A. Rabbani, Moshe Szyf
Targeting methyl-CpG-binding domain protein 2 (Mbd2) towards the development of next generation precision Epi-therapies against metastatic breast cancer
Infection and immunology
- Michael B. Reed, Jesse Shapiro, Nicolas R. Moitessier
A Genome-Wide Approach for Restoring Antibiotic Susceptibility to Drug-Resistant Mycobacterium tuberculosis.
Patient-Oriented Research: Early-Career Investigator
- Julio F Fiore Jr, Stephanie M. Wong, Ipshita Prakash, Liane S. Feldman, Justin Rivard, May Lynn Quan, Sarkis H. Meterissian, Emily G. McDonald, Christine Desbiens, Jad Abou Khalil, Lisa Findlay-Shirras, Allison MacIver, Lawrence Lee, Sahir Bhatnagar, Ramanakumar Agnihotram, Marie-Pascale A. Pomey, Janius Tsang, Elaheh Khorasani
Comparative effectiveness of opioid versus opioid-free post-discharge analgesia after outpatient breast surgery: A randomized controlled trial - Shaifali Sandal, Peter Nugus, Marie-Chantal Fortin, Ann Bugeja, Ekaterina Loban, Justin Gill, Antonia Maioni, Rahul Mainra
System-level approaches to increasing living donor kidney transplantation
BRIDGE GRANTS
- Moshe Ben-Shoshan, Jennifer L. Protudjer, Kate M. Johnson, Julia Upton, Ran D. Goldman
PLEDGE: Policies Laws and Emergency Department Guidelines for Epinephrine auto-injector use - Moshe Ben-Shoshan, Julia Upton, Derek K. Chu
SORT: Safety of OIT in a Randomized Trial - Christian E. Rocheleau
Regulation of C. elegans EGFR trafficking and signaling by Rab and Arf GTPases - Deborah Assayag, Christopher J. Ryerson, Andrea Benedetti, Julie Morisset
Sex and gender based disparities in the treatment of patients with interstitial lung diseases
Learn more on the Canadian Institutes of Health Research (CIHR) website
—Published February 20, 2023
CANADA RESEARCH CHAIRS, SPRING 2022
Tier 1 Canada Research Chairs are awarded to outstanding researchers acknowledged by their peers as world leaders in their fields. Congratulations to three RI-MUHC researchers who earned Tier 1 Chairs in spring 2022! (Competition cycle: 2021-1.)
- Gabriella Gobbi
Brain Repair and Integrative Neuroscience Program, RI-MUHC
Canada Research Chair in Therapeutics for Mental Health, Canadian Institutes of Health Research (CIHR), Tier 1 (New) - Madhukar Pai
Infectious Diseases and Immunity in Global Health Program and Centre for Outcomes Research and Evaluation, RI-MUHC
Canada Research Chair in Epidemiology and Global Health, CIHR, Tier 1 (Renewal) - Cécile Rousseau
Brain Repair and Integrative Neuroscience (BRaIN) Program, RI-MUHC
Canada Research Chair in Preventing Violent Radicalization, Social Sciences and Humanities Research Council (SSHRC), Tier 1 (New)
The Canada Research Chairs Program stands at the centre of a national strategy to make Canada one of the world's top countries in research and development. It invests approximately $311 million per year to attract and retain a diverse cadre of world-class researchers, to reinforce academic research and training excellence in Canadian postsecondary institutions.
Learn more about the competition results for McGill University in the McGill Reporter
—Published Jul. 27, 2022
FRQS SALARY AWARD COMPETITION 2022-2023
Congratulations to researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) who received salary awards from the Fonds de recherche du Québec – Santé (FRQS)!
Distinguished research scholar
- Nitika Pant Pai
Programme de recherche d’implantation global de stratégies numériques innovatrices avec technologies de point de service rapides pour le VIH, les MTS et la COVID-19
Research scholar, Junior 2
- David Labbé
Une nutrition de précision pour induire une thérapie par létalité synthétique ciblée grâce à des stratégies d'oncologie personnalisées pour le cancer de la prostate
Research scholars, Junior 1
- Roberta La Piana
Leucoencéphalopathies génétiques chez l’adulte et leur chevauchement avec les maladies acquises de la myéline : identification de nouvelles gènopathies par l’intégration de données phénotypiques, d’imagerie avancée et de séquençage de nouvelle génération - Julia Valdemarin Burnier
Suivi des altérations génomiques durant la progression tumorale et métastatique à l'aide de biomarqueurs dérivés de biopsies liquides non-invasives
Clinical research scholars, Senior
- Moshe Ben-Shoshan
Allergies aux aliments et aux médicaments: anaphylaxie, taux, causes, gestion et désensibilisation. - Alexandra De Pokomandy
Programme de recherche visant à prévenir ou réduire les conséquences des maladies virales chez les communautés marginalisées - Patricia Fontela
Patients atteints d’infections sévères admis aux soins intensifs : vers une prise en charge optimale fondée sur des données probantes - Bertrand Lebouché
Améliorer l'autogestion et les soins des patients vivant avec le VIH grâce à la santé connectée - Meranda Nakhla
Améliorer les soins de santé et les résultats des enfants et des adolescents atteints de diabète, du diagnostic à la transition vers les soins aux adultes - Donald Vinh
Centre par Excellence pour la Recherche Génétique des Maladies Infectieuses et Immunitaires
Clinical research scholars, Junior 2
- Natalie Dayan
Impact des traitements d'infertilité et les issues maternelles sur la santé des femmes à long terme - Emily McDonald
Générer une base de données probantes pour l'optimisation de la gestion sûre et efficace des médicaments - Ruth Sapir-Pichhadze
La médecine de précision au service des greffés
Clinical research scholars, Junior 1
- Laurence Chapuy
Plasticité des monocytes humains vers des macrophages réparateurs in vivo et in vitro dans les maladies inflammatoires intestinales - Matthew Cheng
Diminuer la morbidité et la mortalité chez les patients atteints de bactériémies au Canada - Roy Dudley
Méthodes avancées d'imagerie à source magnétique pour la détection et la spectroscopie optique peropératoire pour une résection précise de la zone épileptogène dans l'épilepsie focale pédiatrique. - Sinziana Dumitra
Améliorer les résultats oncologiques chez les patients atteints de sarcome en optimisant l'accès et la qualité des soins - Arielle Mendel
La prévention de dommages médicaux dans les maladies rhumatismales systémiques - Shaifali Sandal
Améliorer l'accès à la transplantation rénale: une approche des systèmes de santé - Joshua Vorstenbosch
Comprendre les interactions dynamiques entre l'hôte et les biomatériaux à l'interface tissu-implant
Intersectorial Audace Progam
- Jake Barralet
Visibilité à travers le sang : chirurgie cardiaque mini-invasive sans rayons-X grâce à la robotique intelligente et la vision directe intracardiaque - Stella Daskalopoulou
Trouver ATLANTIS: identification de l'instabilité de la plaque Athérosclérotique à l'aide de techniques d'apprentissage en profondeur
—Published June 13, 2022
FALL 2021 CIHR COMPETITION RESULTS
RI-MUHC teams received $9.5 million in project funding
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will embark on 17 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Fall 2021 Project Grants Competition. The RI-MUHC teams received over $9.5 million in project funding.
Across Canada, the competition has approved 417 research grants plus one bridge grant for a total investment of approximately $325 million. In addition, 105 priority announcement grants were funded for a total amount of over $12 million and 13 supplemental prizes were awarded for a total of $400K.
The CIHR Project Grant program is designed to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.
“We are extremely proud of RI-MUHC grant recipients and their teams for rising to the challenges of the year with this resounding success at the national level,” says Dr. Rhian Touyz, Executive Director and Chief Scientific Officer, RI-MUHC. “Their newly funded projects reflect strengths across the biomedical research spectrum and will, beyond a doubt, lead to exciting developments in health care and the knowledge it relies on, for Canadians and for our global neighbours.”
Congratulations to RI-MUHC grant recipients and their teams!
Project Grants
- Michal Abrahamowicz
New statistical methods for population-based studies of time-varying drug exposures: development, validation, and real-world analyses of drug safety and effectiveness - Faiz Ahmad Khan, Frantz Jean-Louis, Kevin Schwartzman
Chest Radiography and TB Elimination in Nunavik: novel solutions to fill gaps and strengthen regional capacity - Charles Bourque
Mechanical basis for central dysautonomias following head injury in mice - Jun Ding
Unagi: Computational approach driven repurposed drugs for idiopathic pulmonary fibrosis - David Labbé, François Bordeleau
Protein glycation acts as a substrate-dependent tumorigenic molecular switch in prostate cancer - Nathalie Lamarche-Vane
Investigating the mechanisms underlying the Rac1/Cdc42 GTPase regulator CdGAP in breast cancer - Keith Murai
Astrocyte Nanostructure and Function in the Healthy and Diseased Brain - Basil Petrof
Novel therapies for diaphragm failure in muscular dystrophy - Jean-Pierre Routy
Reversing CMV-induced gut damage to reduce inflammation and improve response to vaccine in people living with HIV - Paul Sabatini
Physiologic- and pathophysiologic-responsive brainstem neurons controlling appetite - Rima Slim
Identify novel genes and mechanisms of molar pregnancies and reproductive failure - George Thanassoulis
Addressing knowledge gaps in the use of lipoprotein testing in cardiovascular prevention
Priority announcements
- Nathalie Lamarche-Vane
Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development - Bertrand Lebouché, Kim Engler, Marie-Pascale Pomey, Tibor Schuster
Implementation of a patient portal and tailored patient-reported outcome measures to improve health problem detection and retention in HIV care: The DRHIVE Study - Sara Ahmed, Claudine Auger, Michèle Bleau, Cindy Starnino, Gary Stoopler, Aliki Thomas
Effectiveness of a customized digital platform to increase coordination of care and uptake of evidence based practices: A stepped-wedge design - Jean-Jacques Lebrun
Defining the role of CDK6 and DNA repair pathways in tumorigenesis and identify CDK4/6-dependent synthetic lethal vulnerabilities in triple negative breast cancer
Priority announcement – Genetics (Bridge Funding: Research Priorities)
- Sampath Loganathan
Deciphering the role of metabolic genes in head and neck squamous cell carcinoma
Learn more on the Canadian Institutes of Health Research (CIHR) website
—Published February 10, 2022
CANADA RESEARCH CHAIRS, 2021 COMPETITIONS
Congratulations to RI-MUHC researchers who received Canada Research Chairs! Fall 2021 competition (2020-2 cycle):
Ahmad Haidar
Canada Research Chair in Artificial Pancreas Systems, CIHR, Tier 2 (renewal)
- Research focus: developing artificial pancreas systems – medical devices that automatically regulate glucose levels and are considered the most promising therapy for type 1 diabetes.
Dennis Jensen
Canada Research Chair in Clinical Exercise and Respiratory Physiology, CIHR, Tier 2 (renewal)
- Research focus: advancing knowledge on the mechanisms, measurement and management of activity-related breathlessness and exercise intolerance in people with chronic pulmonary disease.
Ian Watson
Canada Research Chair in Functional Genomics of Melanoma, CIHR, Tier 2 (renewal)
- Research focus: improving on diagnostic and modalities for cutaneous melanoma, the deadliest form of skin cancer, using computational approaches, in vivo models and biochemical techniques studying patient samples, cell lines and melanoma mouse models.
The Canada Research Chairs Program stands at the centre of a national strategy to make Canada one of the world's top countries in research and development. It invests approximately $295 million per year to attract and retain a diverse cadre of world-class researchers, to reinforce academic research and training excellence in Canadian postsecondary institutions.
Learn more about fall 2021 results for McGill University in the McGill Reporter
—Published Jan. 28, 2022
FRQS SALARY AWARD COMPETITION 2021-2022
Congratulations to researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) who received salary awards from the Fonds de recherche du Québec – Santé (FRQS)!
Clinical research scholars
- Jonathan Afilalo
Stratégies novatrices d'évaluation et de traitement de la fragilité chez les personnes âgées atteintes d'une maladie cardiaque - Faiz Ahmad Khan
Développement et évaluation d'interventions pour réduire le fardeau et l'impact de la tuberculose sur les populations vulnérables - Geneviève Bernard
Leucodystrophies: Un Programme de Recherche Translationnelle - Cecilia Costiniuk
La perturbation immunitaire chez les personnes vivantes avec le VIH: interactions avec les réservoirs pulmonaires du VIH et cibles possible d'intervention - Birgit Frauscher (researcher from The Neuro, affiliated with the RI-MUHC BRaIN Program)
Simplifier et améliorer l'évaluation préchirurgicale des patients épileptiques - Thomas Kitzler
Une approche systématique pour étudier les relations génotype-phénotype des nouveaux gènes de la maladie rénale. - Todd C. Lee
Exploiter les réseaux d'essais cliniques pour améliorer le traitement des patients atteints de maladies infectieuses importantes - Isabelle Malhamé
Prédiction et prévention de la morbidité cardiovasculaire grave en grossesse - Thomas Mavrakanas
Maladies cardiovasculaires chez le patient avec insuffisance rénale chronique avancée : données prospectives et étude des avancées thérapeutiques récentes - Maryam Oskoui
Données probantes en amyotrophie spinale reposants sur l’analyse de registres - Giada Sebastiani
Profilage des risques et stratégies de dépistage pour lutter contre l'épidémie silencieuse du foie gras non alcoolique - Jonathan Spicer
Au carrefour de l'immunité tumorale innée et adaptative sur la trajectoire de soins des patients atteints d'un cancer pulmonaire opérable: Comment élargir nos créneaux de tirs? - John Trakadis
L’avancement de la génétique clinique psychiatrique, prendre avantage des omiques et l’apprentissage automatique. - Pia Wintermark
Réparer le cerveau des nouveau-nés: Du laboratoire à leur chevet Institut de recherche du Centre universitaire de santé McGill - George Zogopoulos
Accélérer l’oncologie de précision pour les cancers pancréatico-biliaires: un programme partenaire du Consortium québécois contre le cancer
Research scholars
- Julio Flavio Fiore Junior
La voie du rétablissement après la chirurgie: Stratégies contemporaines pour mesurer et améliorer les résultats postopératoires. - Wei-Hsiang Huang
Mécanisme et thérapie de l'hyperexcitabilité neurale dans les troubles du spectre autistique - Ivan Litvinov
Élucider la pathogenèse moléculaire, améliorer le diagnostic ainsi que la prise en charge des patients atteints du lymphome cutané à cellules T, mélanome et autres cancers de la peau. - Tina Montreuil
Quantification de l'impact d'interventions préventives et identification de l’impact de symptômes anxieux et dépressifs périnataux sur le développement socioémotionnel de l’enfant - Derek Rosenzweig
Nouvelles approches de délivrance thérapeutique pour une régénération améliorée des tissus musculosquelettiques après resection tumorale, traumatisme ou infection. - Jeremy Van Raamsdonk
Utilisation de la génétique pour comprendre la biologie du vieillissement et de la pathogenèse des maladies neurodégénératives. - Bettina Willie
Causes, détection et traitement des maladies causant des fragilités osseuses
—Published May 10, 2021
FALL 2020 CIHR COMPETITION RESULTS
RI-MUHC teams received $6.9 million in project funding and $2 million more for COVID-19 research
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will embark on 11 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Fall 2020 Project Grants Competition. The RI‑MUHC teams received $6.9 million in project funding.
Across Canada, the competition has approved 354 research grants for a total investment of approximately $274 million. In addition, over $9.5 million was awarded for 97 priority announcement bridge grants and $296K for 11 supplemental prizes.
Exceptionally this year, four RI-MUHC researchers were also awarded operating grants to tackle evidence gaps in COVID-19 research for a total of close to $2 million more in project funding. Across Canada, the CIHR has invested $25.2 million in 52 projects in this stream.
The CIHR Project Grant program is designed to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.
Congratulations to RI-MUHC grant recipients and their teams!
Project Grants
- Jean Bourbeau, Jeffrey R. Brook, Benjamin M. Smith
Air pollution, climate and COPD: acute and long-term impacts in Canadian populations - Matthew P. Cheng, Nick Daneman, Jennie Johnstone, Todd C. Lee
The S. aureus Network Adaptive Platform Trial (SNAP) Canada: A Randomized Controlled Trial for Penicillin-susceptible, Methicillin-susceptible, and Methicillin-resistant Staphylococcus aureus Bloodstream Infections in Hospitalized Patients - Yen-I Chen, Alan N. Barkun
Endoscopic ultrasound-guided biliary drainage (EUS-BD) of first intent with a lumen apposing metal stent vs. endoscopic retrograde cholangiopancreatography (ERCP) in the management of patients with malignant distal biliary obstruction: a multi-centre randomized controlled trial (ELEMENT trial) - Natalie Dayan, Robert W. Platt
Beyond survival: examining health of mothers after severe maternal morbidity in Canada (the BEYOND project) - Alexandra De Pokomandy
Creating a learning health system to improve cancer prevention in people living with HIV - Maia Kokoeva
The leptin receptor expressing pericyte links obesity to neuroinflammation - Maia Kokoeva
Could mitotic senescence in NG2-glia explain the remyelination deficit in MS? - Jun-Li Liu
Matricellular protein CCN5/WISP2 mediates a synergistic stimulation of pancreatic beta-cell expansion by IGF-I and Wnt signaling - Anie Philip, Andrew C. Leask
Characterization of a novel anti-fibrotic peptide for the treatment of scleroderma - Abhinav Sharma, James M. Brophy, Nandini Dendukuri, Ariane Marelli, Harriette Van Spall
Identification and prediction of sex-specific cardiovascular causes of death and outcomes in people with diabetes mellitus post myocardial infarction (SCD-DM-MI)
Priority announcements
- Andrea Benedetti, Brett D. Thombs
Statistical Methodology for Prediction Modelling to Improve Depression Screening with Individualized Risk Estimates in the Context of Individual Participant Data Meta-analysis
COVID-19 Operating Grants
- Alan Barkun
Digestive endoscopy in the era of COVID19: An opportunity for optimizing timely equitable care during the pandemic and beyond - Maziar Divangahi
Developing a novel vaccine against COVID-19 - Nitika Pant Pai
Evaluation of a digital, rapid self-sampling strategy for individuals with suspected COVID-19 infection in South Africa and India - Cecile Rousseau
Social polarization and behavioral intentions during the COVID-19 pandemic: A multi-site study of risk and protective factors in Canadian youth
Learn more on the Canadian Institutes of Health Research (CIHR) website
—Published March 19, 2021
CANADA RESEARCH CHAIRS, 2020 COMPETITIONS
Congratulations to RI-MUHC researchers who received Canada Research Chairs!
Fall 2020 competition (2019-2 cycle):
- Marie Brossard-Racine, Canada Research Chair in Brain and Child Development, CIHR, Tier 2 (New)
Spring 2020 competition (2019-1 cycle):
- Shirin Abbasinejad Enger, Canada Research Chair in Medical Physics, CIHR, Tier 2 (New)
- Stefanie Blain-Moraes, Canada Research Chair in Biosignal Interaction and Personhood Technology, CIHR, Tier 2 (New)
- David Buckeridge, Canada Research Chair in Population Health Informatics, CIHR, Tier 1 (New)
- Nada Jabado, Canada Research Chair in Pediatric Oncology, CIHR, Tier 1 (New)
- Dick Menzies, Canada Research Chair in Tuberculosis Research, CIHR, Tier 1 (New)
We also congratulate two researchers from The Neuro (Montreal Neurological Institute–Hospital) affiliated with the Brain Repair and Integrative Neuroscience (BRaIN) Program at the RI-MUHC:
- Boris Bernhardt, Canada Research Chair in Cognitive Neuroinformatics of Healthy and Diseased Brains, CIHR, Tier 2 (New)
- Robert Zatorre, Canada Research Chair in Auditory Cognitive Neuroscience, CIHR, Tier 1 (New)
The Canada Research Chairs Program stands at the centre of a national strategy to make Canada one of the world's top countries in research and development. It invests approximately $295 million per year to attract and retain a diverse cadre of world-class researchers, to reinforce academic research and training excellence in Canadian postsecondary institutions.
Learn more:
Newswire, Social Sciences and Humanities Research Council of Canada, Dec. 16, 2020
McGill Reporter, fall 2020 results
—Published Aug. 6, 2020; updated Jan. 15, 2021
FALL 2019 CIHR COMPETITION RESULTS
Researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) will be conducting 25 new projects designed to accelerate discoveries of benefit to human health, thanks to the Canadian Institutes of Health Research (CIHR) Fall 2019 Project Grants Competition. The RI-MUHC teams received over $16 million in project funding.
Across Canada, the competition has approved 385 research grants and 4 bridge grants for a total investment of approximately $275 million. In addition, over $7 million was awarded for 74 priority announcement bridge grants.
The CIHR Project Grant program is designed to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.
Congratulations to RI-MUHC grant recipients and their teams!
Project Grants
- Faiz Ahmad Khan, Glenda Sandy, Christopher Fletcher, Neil Andersson
Community Health Workers in Tuberculosis Prevention & Care Services in Nunavik - Carolyn Baglole, Ilan Azuelos
Prognostic and Therapeutic Utility of Human Antigen R (HuR) in Fibrosis - Swneke Bailey
Investigating the Molecular Determinants of Peritoneal Metastasis from Gastro-Esophageal Adenocarcinomas - Geneviève Bernard
Unraveling the molecular basis of novel forms of hypomyelinating leukodystrophies - Nancy Braverman
Developing retinal gene augmentation therapy for Zellweger Spectrum Disorder - Pnina Brodt
Regulatory circuits controlling the immune microenvironment of liver metastases - Stella Daskalopoulou
Early Prediction of preeclampsia Using arteriaL Stiffness in high-risk prEgnancies; a multinational study (PULSE) - Samuel David
Ferroptosis-mediated damage in Chronic EAE: implications for Progressive MS - Maziar Divangahi
Targeting the eicosanoid/macrophage axis to enhance host defense against influenza virus infection - Maziar Divangahi
Reprogramming HSCs to generate protective trained immunity against TB - Julio Fiore Jr
Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis - Jacques Genest Jr
Familial Hypercholesterolemia in Canada: Precision and Personalized Approaches to Increase Identification and Improve Clinical outcomes - Wassim Kassouf
Implication of neutrophil extracellular traps in the efficacy of bladder-sparing therapy in muscle invasive bladder cancer - Ivan Litvinov
Ectopic reactivation of normally silenced germ cell programs contributes to genomic instability, carcinogenesis and cancer progression in Cutaneous T-Cell Lymphomas (CTCL). - Monzur Murshed
Understanding the mechanism of vascular elastocalcinosis and its prevention by MGP - Basil Petrof
Understanding the basis of diaphragmatic weakness in critical illness - Giada Sebastiani
The role of fatty liver in the epidemic of advanced chronic liver disease among people living with HIV - Elena Torban
Actin regulation of ciliogenesis: unraveling novel mechanisms of human ciliopathies caused by mutations in the PCP effector genes - Simon Wing
USP19 in metabolism - mechanisms and translation
Priority announcements
- Stéphanie Chevalier
A novel multimodal intervention for surgical prehabilitation of patients with lung cancer - Andrey Cybulsky
Defining the role of ER stress in glomerular disease: identification of new therapeutic and diagnostic targets - Maia Kokoeva
Could mitotic exhaustion of NG2-glia explain the remyelination deficit in MS? - Ivan Litvinov
Prize: Early Career Investigator in Cancer - Dan Poenaru
WeChoose: a mixed-methods study for developing a personalized risk communication tool in pediatric surgery - Myriam Srour, Dorothy Barthelemy
The physiological, molecular and genetic mechanisms underlying lateralization of motor control
Learn more on the Canadian Institutes of Health Research (CIHR) website
—Published January 30, 2020