null James Brophy, MD, PhD

Senior Scientist, RI-MUHC, 5252 de Maisonneuve site

Cardiovascular Health Across the Lifespan Program

Centre for Outcomes Research and Evaluation

Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

Department of Medicine, Division of Cardiology, MUHC



cardiovascular epidemiology • pharmacoepideiology • Bayesian statistics

Research Focus

My research interests are eclectic and include outcomes research, pharmacoepidemiology, Bayesian statistics, health technology assessment, economic analyses and clinical research, which are supported partially through an FRQS chair in health technology assessment and evidence-based medicine.

Selected Publications

Click on Pubmed to see my current publications list

  • Bayesian Interpretation of the EXCEL Trial and Other Randomized Clinical Trials of Left Main Coronary Artery Revascularization. Brophy JM. JAMA Intern Med. 2020 Jul 1;180(7):986-992. doi: 10.1001/jamainternmed.2020.1647. PMID: 32478838.

  • Variability in High-Sensitivity Cardiac Troponin T Testing in Stable Patients With and Without Coronary Artery Disease. Brophy JM, Dagenais GR, Boyer L, Garcia-Labbé D, Bogaty P.Can J Cardiol. 2019 Nov;35(11):1505-1512. doi: 10.1016/j.cjca.2019.08.022. Epub 2019 Aug 22. PMID: 31679620.

  • Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation. Etminan M, Sodhi M, Ganjizadeh-Zavareh S, Carleton B, Kezouh A, Brophy JM. J Am Coll Cardiol. 2019 Sep 17;74(11):1444-1450. doi: 10.1016/j.jacc.2019.07.035. PMID: 31514945.