null Alan Barkun, MDCM, M.Sc.

Senior Scientist, RI-MUHC, Montreal General Hospital site

Surgical and Interventional Sciences Program

Centre for Outcomes Research and Evaluation

Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

Department of Medicine, Division of Gastroenterology, MUHC



digestive endoscopy • technology evaluation • knowledge translation • gastrointestinal bleeding • bilio-pancreatic diseases

Research Focus

My research focuses on assessing effectiveness and costs of emerging and established techniques that provide diagnosis and allow therapy for patients afflicted with digestive conditions such as ulcer bleeding, colorectal cancer (including screening), and both biliary and pancreatic diseases. I also study the development of guidelines to incorporate these techniques in everyday practice and monitor how these are taken up and applied to enhance contemporary standards of care.

Selected Publications

Click on Pubmed to see my current publications list

  • Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group. Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M. Ann Intern Med. 2019 Dec 3;171(11):805-822. doi: 10.7326/M19-1795. Epub 2019 Oct 22. PMID: 31634917.

  • TC-325 hemostatic powder versus current standard of care in managing malignant GI bleeding: a pilot randomized clinical trial. Chen YI, Wyse J, Lu Y, Martel M, Barkun AN. Gastrointest Endosc. 2020 Feb;91(2):321-328.e1. doi: 10.1016/j.gie.2019.08.005. Epub 2019 Aug 19. PMID: 31437456.

  • The Bowel CLEANsing National Initiative: A Low-Volume Same-Day Polyethylene Glycol (PEG) Preparation vs Low-Volume Split-Dose PEG With Bisacodyl or High-Volume Split-Dose PEG Preparations-A Randomized Controlled Trial. Barkun AN, Martel M, Epstein IL, Hallé P, Hilsden RJ, James PD, Rostom A, Sey M, Singh H, Sultanian R, Telford JJ, von Renteln D. Am J Gastroenterol. 2020 Dec;115(12):2068-2076. doi: 10.14309/ajg.0000000000000760. PMID: 32740079.

  • Use of Doppler Probe in Nonvariceal Upper-Gastrointestinal Bleeding Is Less Costly and More Effective Than Standard of Care. Barkun AN, Adam V, Wong RCK. Clin Gastroenterol Hepatol. 2019 Nov;17(12):2463-2470. doi: 10.1016/j.cgh.2019.02.016. Epub 2019 Feb 14. PMID: 30772584.

  • Systematic review with meta-analysis: limited benefits from early colonoscopy in acute lower gastrointestinal bleeding. Kherad O, Restellini S, Almadi M, Strate LL, Ménard C, Martel M, Roshan Afshar I, Sadr MS, Barkun AN. Aliment Pharmacol Ther. 2020 Sep;52(5):774-788. doi: 10.1111/apt.15925. Epub 2020 Jul 22. Review. PMID: 32697886.