High and super-resolution microscopy for cell, tissue and intravital imaging
The Molecular Imaging Platform is one of the Centre for Translational Biology (CTB) Technology Platforms at the Research Institute of the McGill University Health Centre (RI-MUHC). The state-of-the-art light microscopy facility specializes in cell, tissue and intravital imaging.
The platform houses multiple diversified and sophisticated systems, including epifluorescent microscopes for basic applications and live cell imaging (Ca2+ and ratiometric imaging); confocal microscopes for 2D and 3D imaging; fluorescence correlation spectroscopy (FCS); super-resolution imaging (SIM, PALM and dSTORM); and live cell imaging with photo manipulation.
The platform has the first multi-photon microscope with dual IR-OPO lasers for intravital imaging in Canada. Other instruments include high-content screening/imaging (HCS/HCI) microscopes for medium-size screening and imaging as well as plate readers for multimodality applications (label-free, absorbance, bioluminescence and fluorescence).
Applications and services
Below are typical applications performed in the Molecular Imaging platform:
- Confocal imaging
- Super-resolution imaging
- Live cell imaging
- Intravital and deep tissue imaging
- High-content imaging and screening
- Other services
Centre for Translational Biology Technology Platforms
The CTB Technology Platforms provide access to state-of-the-art technologies and instrumentation as well as top-level scientific expertise and training. Watch the video, explore the links below, and prepare to accelerate your research!