null Catherine Goudie, MD, FRCPC
cancer predisposition syndrome • pediatric • oncology • genetics • decision support tool • eHealth • health economics • health resource allocation • tumor surveillance protocols • second malignancies
My research program focuses on cancer predisposition syndromes that present in childhood. A cancer predisposition syndrome is a genetic condition that increases a person’s risk of developing one or more cancers in their lifetime. Our team has developed an eHealth decision-support tool, called MIPOGG (McGill Interactive Pediatric OncoGenetic Guidelines), that helps doctors recognize their patients with cancer who need to be referred to Genetics because they are at increased risk of having a cancer predisposition syndrome. MIPOGG is an ehealth tool containing 90 tumour-specific algorithms that use clinical, family history and tumour features to generate a recommendation for genetic referral based on the risk of a cancer predisposition syndrome.
C.Goudie, F. Hannah-Shmouni, M. Kavak, C. A. Stratakis, W.Foulkes. (2018). Endocrine Tumour Syndromes in Children and Adolescents. Endocrine-Related Cancer. 25(8): 221-244.
Goudie C, Witkowski L, Vairy S, McCluggage WG, Foulkes WD. (2018). Paediatric Ovarian Tumours and Their Associated Cancer Susceptibility Syndromes. Journal of Medical Genetics. 55(1): 1-10.
Goudie C, Cullinan N, Villani A, Mathews N, van Engelen K, Malkin D, Foulkes W, Irwin M. (2018). Retrospective Evaluation of a Decision Support Algorithm (MIPOGG) for Genetic Referrals in Children with Neuroblastic Tumors. Pediatric Blood and Cancer. -: e27390.
Goudie C, Coltin H, Witkowski L, Mourad S, Malkin D, Foulkes WD. (2016). The McGill Interactive Pediatric OncoGenetic Guidelines (MIPOGG): An approach to identifying pediatric oncology patients most likely to benefit from a genetic evaluation. Pediatric Blood and Cancer, Special Report. 64(8): e26411 - e26411.
Goudie C and Malkin D. (2016). Cancer Predisposition Syndromes 101: A case history and review of the challenges. University of Toronto Medical Journal. 94: 25-31.