null Isabelle Malhamé, MD, M.Sc.

Junior Scientist, RI-MUHC

Cardiovascular Health Across the Lifespan Program

Centre for Outcomes Research and Evaluation

Assistant Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University



pregnancy • postpartum • severe maternal morbidity • maternal mortality • preeclampsia • peripartum cardiomyopathy • venous thromboembolism

Research Focus

The overarching aim of my research program is to improve maternal health by reducing pregnancy-related severe morbidity, including from cardiovascular and thromboembolic complications. My program focuses on the following research themes: epidemiology and risk prediction; innovation in the diagnosis and management of high-risk conditions; and quality improvement and patient safety.

Selected Publications

Click on Pubmed to see my current publications list

  • Malhamé I, Czuzoj-Shulman N, Abenhaim H, et al. Cardiovascular Severe Maternal Morbidity and Mortality at Delivery in the United States. JACC Adv. null2022, 1 (4) 1–10.

  • Malhamé I, Raker CA, Hardy EJ, Spalding H, Bouvier BA, Hurlburt H, Vrees R, Daskalopoulou SS, Nerenberg K, Savitz DA, Mehta N, Danilack VA. Development and Internal Validation of a Risk Prediction Model for Acute Cardiovascular Morbidity in Preeclampsia. Can J Cardiol. 2022 Oct;38(10):1591-1599. doi: 10.1016/j.cjca.2022.05.007. Epub 2022 Jun 13. PMID: 35709932.

  • Malhamé I, Knight M, D'Souza R. Initial Steps in Developing and Implementing a Canadian Obstetric Survey System (CanOSS) for Severe Maternal Morbidity. J Obstet Gynaecol Can. 2022 Jun;44(6):637-638. doi: 10.1016/j.jogc.2022.02.002. PMID: 35691680.

  • Malhamé I, Dong S, Syeda A, Ashraf R, Zipursky J, Horn D, Daskalopoulou SS, D'Souza R. The use of loop diuretics in the context of hypertensive disorders of pregnancy: a systematic review and meta-analysis. J Hypertens. 2023 Jan 1;41(1):17-26. doi: 10.1097/HJH.0000000000003310. Epub 2022 Nov 2. PMID: 36453652.

  • Malhamé I, Danilack VA, Raker CA, Hardy EJ, Spalding H, Bouvier BA, Hurlburt H, Vrees R, Savitz DA, Mehta N. Cardiovascular severe maternal morbidity in pregnant and postpartum women: development and internal validation of risk prediction models. BJOG. 2021 Apr;128(5):922-932. doi: 10.1111/1471-0528.16512. Epub 2020 Nov 4. PMID: 32946639.