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null Moshe Ben-Shoshan, MD, M.Sc.

Scientist, RI-MUHC, Glen site

Infectious Diseases and Immunity in Global Health Program

Centre for Outcomes Research and Evaluation

Associate Professor, Department of Pediatrics, Faculty of Medicine and Health Sciences, McGill University

Department of Pediatrics, Division of Allergy/Immunology/Dermatology, MUHC

 

Keywords

Food allergy • anaphylaxis • immunodeficiency • chronic urticaria

Research Focus

My research focuses on the prevalence and potential determinants of food allergies and anaphylaxis (severe allergic reactions) in children. In addition, I have established a registry aiming to assess triggers and management of different forms of chronic urticaria, or hives. I also conduct research on primary immunodeficiencies, exploring the ability of children's immune systems to fight infectious disease. In collaboration with Dr. Ann Clarke at the Montreal General Hospital of the MUHC, I conducted the first nationwide Canadian study to determine the prevalence of severe food allergies. The results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates. In recent years I have led the first Canada-wide anaphylaxis registry exploring the societal burden, triggers, management and natural history of anaphylaxis in Canadians.

Selected Publications

Click on Pubmed to see my current publications list

  • Assessing Pediatric Cephalosporin Allergic Reactions Through Direct Graded Oral Challenges. Sillcox C, Gabrielli S, O'Keefe A, McCusker C, Abrams EM, Eiwegger T, Atkinson A, Kim V, Copaescu AM, Ben-Shoshan M. J Allergy Clin Immunol Pract. 2023 Oct 11:S2213-2198(23)01125-X. doi: 10.1016/j.jaip.2023.10.009. Online ahead of print. PMID: 37832819.

  • Managing anaphylaxis: Epinephrine, antihistamines, and corticosteroids: More than 10 years of Cross-Canada Anaphylaxis REgistry data. Delli Colli L, Al Ali A, Gabrielli S, Delli Colli M, Mule P, Lawson B, Clarke AE, Morris J, Gravel J, Lim R, Chan ES, Goldman RD, O'Keefe A, Gerdts J, Chu DK, Upton J, Hochstadter E, Bretholz A, McCusker C, Zhang X, Benor S, Simons E, Abrams EM, Protudjer JLP, Ben-Shoshan M. Ann Allergy Asthma Immunol. 2023 Dec;131(6):752-758.e1. doi: 10.1016/j.anai.2023.08.606. Epub 2023 Sep 7. PMID: 37689113.

  • Prevalence, Management, and Anaphylaxis Risk of Cold Urticaria: A Systematic Review and Meta-Analysis. Prosty C, Gabrielli S, Le M, Ensina LF, Zhang X, Netchiporouk E, Ben-Shoshan M. J Allergy Clin Immunol Pract. 2022 Feb;10(2):586-596.e4. doi: 10.1016/j.jaip.2021.10.012. Epub 2021 Oct 18. PMID: 34673287.

  • Differentiating Between β-Lactam-Induced Serum Sickness-Like Reactions and Viral Exanthem in Children Using a Graded Oral Challenge. Delli Colli L, Gabrielli S, Abrams EM, O'Keefe A, Protudjer JLP, Lavine E, Pitt T, Atkinson A, Eiwegger T, McCusker C, Ben-Shoshan M. J Allergy Clin Immunol Pract. 2021 Feb;9(2):916-921. doi: 10.1016/j.jaip.2020.08.047. Epub 2020 Sep 6. PMID: 32898711.

  • Assessing the Diagnostic Properties of a Graded Oral Provocation Challenge for the Diagnosis of Immediate and Nonimmediate Reactions to Amoxicillin in Children. Mill C, Primeau MN, Medoff E, Lejtenyi C, O'Keefe A, Netchiporouk E, Dery A, Ben-Shoshan M. JAMA Pediatr. 2016 Jun 6;170(6):e160033. doi: 10.1001/jamapediatrics.2016.0033. Epub 2016 Jun 6. PMID: 27043788.