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angle-left Giada Sebastiani, MD

Scientist, RI-MUHC , 5252 de Maisonneuve

Infectious Diseases and Immunity in Global Health Program

Centre for Outcomes Research and Evaluation

Associate Professor, Department of Medicine, Faculty of Medicine, McGill University

Department of Medicine, Division of Gastroenterology, MUHC

 

Keywords


fatty liver • serum fibrosis biomarkers • hepatitis B • hepatitis C • HIV

Research Focus


My research focuses on screening for liver disease and fatty liver of at risk populations, including HIV+ patients, patients with inflammatory bowel disease, liver transplant recipients. To conduct these studies, I employ a non-invasive machine, which is ultrasound based, named Fibroscan. Moreover, I am conducting interventional trials to reduce the fatty liver by vitamin E and switch to less hepatotoxic drugs.

Selected Publications


Click on Pubmed to see my current publications list

  • MRI cine-tagging of cardiac-induced motion for noninvasive staging of liver fibrosis. Lefebvre T, Petitclerc L, Hébert M, Bilodeau L, Sebastiani G, Olivié D, Gao ZH, Sylvestre MP, Cloutier G, Nguyen BN, Gilbert G, Tang A. J Magn Reson Imaging. 2019 Oct 12. doi: 10.1002/jmri.26935. [Epub ahead of print]. PMID: 31605412.

  • Nonalcoholic fatty liver disease in HIV: the (not so) new kid on the block? Krahn T, Sebastiani G. Clin Infect Dis. 2019 Sep 20. pii: ciz929. doi: 10.1093/cid/ciz929. [Epub ahead of print] No abstract available. PMID: 31538647.

  • Prospective comparison of transient, point shear wave, and magnetic resonance elastography for staging liver fibrosis.Lefebvre T, Wartelle-Bladou C, Wong P, Sebastiani G, Giard JM, Castel H, Murphy-Lavallée J, Olivié D, Ilinca A, Sylvestre MP, Gilbert G, Gao ZH, Nguyen BN, Cloutier G, Tang A.Eur Radiol. 2019 Jul 5. doi: 10.1007/s00330-019-06331-4. [Epub ahead of print]. PMID: 31278577.

  • Clinical significance of elevated liver transaminases in HIV-infected patients Cai J, Osikowicz M, Sebastiani G. AIDS. 2019 Jul 1;33(8):1267-1282. doi: 10.1097/QAD.0000000000002233. PMID: 31008799.

  • HIV, Elevated Transaminases, Fatty Liver: The Perfect Storm? Cai J, Sebastiani G. J Acquir Immune Defic Syndr. 2019 May 1;81(1):e23-e25. doi: 10.1097/QAI.0000000000001984. No abstract available. PMID: 30964807.