null Maryam Oskoui, MD, MSc
epidemiology • clinical trials • patient registries • neuromuscular disorders • pediatric neurology
My research focus is in pediatric neuromuscular disorders with the aim to improve individual outcomes. My research team is involved in clinical trials and we also use patient registries to study the real-world effect of new treatments and changes in care. We are working with patient partners to develop more sensitive outcome measures to capture change that is meaningful to them. I am a co-principal investigator on a CIHR Strategy for Patient Oriented Research (SPOR) Innovative Clinical Trial focused on treatable rare diseases. We are currently developing an exergaming intervention for youth with spinal muscular atrophy that will be launched through a registry-based clinical trial in the coming years. We are also studying, using specialized imaging techniques, how brain development differs in spinal muscular atrophy to develop future interventions to optimize healthy developmental trajectories. I also serve as an evidence-based methodologist for the American Academy of Neurology.
Servais L, Baranello G, Scoto M, Daron A, Oskoui M. Therapeutic interventions for spinal muscular atrophy: preclinical and clinical development opportunities. Expert Opinion On Investigational Drugs. Mar 2021. Doi: 10.1080/13543784.2021.1904889.
Walter MC, Chiriboga C, Duong T, Goemans N, Mayhew A, Ouillade L, Oskoui M, Quinlivan R, Vázquez-Costa JF, Vissing J, Servais L. Improving Care and Empowering Adults Living with SMA: A Call to Action in the New Treatment Era. J Neuromuscul Dis. 2021 Feb 24. PMID: 33646175.
Oskoui M, Kim DH, Mentis GZ, De Vivo DC. Transient hyperreflexia: An early diagnostic clue in later-onset spinal muscular atrophy. Neurol Clin Pract. 2020 Dec;10(6):e66-e67.
Fortin O, Ng P, Dorais M, Koclas L, Pigeon N, Shevell M, Oskoui M. Emergency department use in children with cerebral palsy: A Data Linkage Study. Can J Neurol Sci. 2020 2020 Oct 7;1-6.
Oskoui M, Ng P, Zaman M, Buckley D, Kirton A, van Rensburg E, Wood E, Shevell M, Majnemer A. Factors Associated with Complementary and Alternative Therapy Use in Children with Cerebral Palsy. Can J Neurol Sci. 2020 Aug. Online ahead of print. 1-21.