null Andrea Benedetti, PhD

Scientist, RI-MUHC , 5252 de Maisonneuve

Translational Research in Respiratory Diseases Program

Centre for Outcomes Research and Evaluation

Associate Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

Department of Medicine, Division of Respiratory Medicine, MUHC



biostatistics • epidemiology • tuberculosis • chronic obstructive pulmonary disease (COPD) • individual patient data meta analysis

Research Focus

My research focuses on statistical methodology. I hope to help researchers make the best use of their data by developing and advancing biostatistical methods. In particular, I am interested in methods for analyzing individual patient data meta analysis, smoothing particularly in the context of mixed models, and methods to analyze clustered or longitudinal data. My collaborative work focuses on depression screening and respiratory health. I have active collaborations with researchers studying tuberculosis, chronic obstructive pulmonary disease, asthma, etc.

Selected Publications

Click on Pubmed to see my current publications list

  • Levis B, Benedetti A, Ioannidis JPA, Sun Y, Negeri Z, He C, Wu Y, Krishnan A, Bhandari PM, Neupane D, Imran M, Rice DB, Riehm KE, Saadat N, Azar M, Boruff J, Cuijpers P, Gilbody S, Kloda LA, McMillan D, Patten SB, Shrier I, Ziegelstein RC, Alamri SH, Amtmann D, Ayalon L, Baradaran HR, Beraldi A, Bernstein CN, Bhana A, Bombardier CH, Carter G, Chagas MH, Chibanda D, Clover K, Conwell Y, Diez-Quevedo C, Fann JR, Fischer FH, Gholizadeh L, Gibson LJ, Green EP, Greeno CG, Hall BJ, Haroz EE, Ismail K, Jetté N, Khamseh ME, Kwan Y, Lara MA, Liu SI, Loureiro SR, Löwe B, Marrie RA, Marsh L, McGuire A, Muramatsu K, Navarrete L, Osório FL, Petersen I, Picardi A, Pugh SL, Quinn TJ, Rooney AG, Shinn EH, Sidebottom A, Spangenberg L, Tan PLL, Taylor-Rowan M, Turner A, van Weert HC, Vöhringer PA, Wagner LI, White J, Winkley K, Thombs BD. Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis. J Clin Epidemiol. 2020 Jun;122:115-128.e1. doi: 10.1016/j.jclinepi.2020.02.002. Epub 2020 Feb 24. PMID: 32105798.

  • McGrath S, Sohn H, Steele R, Benedetti A. Meta-analysis of the difference of medians. Biom J. 2020 Jan;62(1):69-98. doi: 10.1002/bimj.201900036. Epub 2019 Sep 25. PMID: 31553488.

  • Menzies D, Adjobimey M, Ruslami R, Trajman A, Sow O, Kim H, Obeng Baah J, Marks GB, Long R, Hoeppner V, Elwood K, Al-Jahdali H, Gninafon M, Apriani L, Koesoemadinata RC, Kritski A, Rolla V, Bah B, Camara A, Boakye I, Cook VJ, Goldberg H, Valiquette C, Hornby K, Dion MJ, Li PZ, Hill PC, Schwartzman K, Benedetti A. Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults. N Engl J Med. 2018 Aug 2;379(5):440-453. doi: 10.1056/NEJMoa1714283. PMID: 30067931.

  • Levis B, Benedetti A, Thombs BD. Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis. BMJ. 2019 Apr 9;365:l1476. doi: 10.1136/bmj.l1476. PMID: 30967483.

  • McGrath S, Zhao X, Qin ZZ, Steele R, Benedetti A. One-sample aggregate data meta-analysis of medians. Stat Med. 2019 Mar 15;38(6):969-984. doi: 10.1002/sim.8013. Epub 2018 Nov 20. PMID: 30460713.