tuberculosis • biostatistics • epidemiology • respiratory disease • global health
My research focuses on clinical and epidemiologic aspects of tuberculosis. My clinical research involves diagnosis of latent as well as active TB: evaluating new tests or strategies to diagnose these conditions. In terms of treatment my interest lies in evaluation through randomized trials and epidemiologic studies. I am interested in occupational tuberculosis, particularly among healthcare workers and prevention of TB transmission within hospitals and other healthcare facilities. I am also interested in tuberculosis in disadvantaged populations, including aboriginal populations in Canada.
Menzies D1, Long R, Trajman A, Dion MJ, Yang J, Al Jahdali H, Memish Z, Khan K, Gardam M, Hoeppner V, Benedetti A, Schwartzman K. Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection: a randomized trial. Ann Intern Med. 2008 Nov 18;149(10):689-97. PMID: 19017587.
Oxlade O1, Schwartzman K, Benedetti A, Pai M, Heymann J, Menzies D. Developing a tuberculosis transmission model that accounts for changes in population health. Med Decis Making. 2011 Jan-Feb;31(1):53-68. doi: 10.1177/0272989X10369001. Epub 2010 Jun 2. PMID: 20519452.
Menzies D1, Nahid P. Update in tuberculosis and nontuberculous mycobacterial disease 2012. Am J Respir Crit Care Med. 2013 Oct 15;188(8):923-7. doi: 10.1164/rccm.201304-0687UP. PMID: 24127799.
Denkinger CM1, Pai M, Patel M, Menzies D. Gamma interferon release assay for monitoring of treatment response for active tuberculosis: an explosion in the spaghetti factory. J Clin Microbiol. 2013 Feb;51(2):607-10. doi: 10.1128/JCM.02278-12. Epub 2012 Nov 21. PMID: 23175268.
Bastos ML, Hussain H, Weyer K, Garcia-Garcia L, Leimane V, Leung CC, Narita M, Penã JM, Ponce-de-Leon A, Seung KJ, Shean K, Sifuentes-Osornio J, Van der Walt M, Van der Werf TS, Yew WW, Menzies D; Collaborative Group for Meta-analysis of Individual Patient Data in MDR-TB. Treatment outcomes of patients with multidrug-resistant and extensively drug-resistant tuberculosis according to drug susceptibility testing to first- and second-line drugs: an individual patient data meta-analysis. Clin Infect Dis. 2014 Nov 15;59(10):1364-74. doi: 10.1093/cid/ciu619. Epub 2014 Aug 5. PMID: 25097082.