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My research focuses on interventions related to polypharmacy, safe and effective prescribing, and medication rationalization. A number of my studies relating to the appropriate use of hospital resources, tests and investigations have been published in high impact peer-reviewed journals and several relating to safer prescribing in older adults were featured recently in the media. I supervise postgraduate students in the field of medication safety and have received funding from the CIHR, the Centre for Ageing and Brain Health Innovation, the Canadian Frailty Network and, locally, from the McGill Interdisciplinary Initiative in Infection and Immunity (MI-4).
Boulware DR, Pullen MF, Bangdiwala AS, Pastick KA, Lofgren SM, Okafor EC, Skipper CP, Nascene AA, Nicol MR, Abassi M, Engen NW, Cheng MP, LaBar D, Lother SA, MacKenzie LJ, Drobot G, Marten N, Zarychanski R, Kelly LE, Schwartz IS, McDonald EG, Rajasingham R, Lee TC, Hullsiek KH. A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19. N Engl J Med. 2020 Jun 3. doi: 10.1056/NEJMoa2016638. Online ahead of print. PMID: 32492293.
Ross S, Wu P, Antique A, Papillon-Ferland L, Tamblyn R, Lee TC, McDonald EG. Adverse Drug Events in Older Adults: A Review of Adjudication Methods in Deprescribing Clinical Trials. JAGS. March 6th 2020 epub ahead of print. PMID: 32142161.
McDonald EG, Dendukuri N, Frenette C et al., The Impact of Private Rooms on Common Healthcare Associated Infections: A Time Series Analysis of a Complete Hospital move. JAMA Internal Medicine. Online First Aug 19, 2019. PMID: 31424489.
McDonald EG, Wu P, Rashidi B et al., The MedSafer study: a controlled trial of an electronic decision support tool for deprescribing in acute care. Journal of American Geriatrics Society. Epub 2019 Jun 27. PMID: 31250427.
McDonald EG, Milligan J, Frenette C, Lee TC. Continuous proton pump inhibitor therapy and the associated risk of recurrent Clostridium Difficile. JAMA int med, 2015 May;175(5):784-91. PMID: 25730198.