null Brett Burstein, MDCM, PhD, MPH, FRCPC, FAAP
Febrile young infants • serious bacterial infections • fever • sepsis • viral testing
Fever among infants in the first three months of life remains one of the most commonly encountered clinical problems in all of pediatric healthcare. Although the majority of these infants have self-limited viral illnesses, approximately 10% harbour potentially life-threatening serious bacterial infections. High-risk infants cannot be identified on the basis of history and physical exam alone. Decisions must be made regarding the extent of investigations as well as the need for antibiotic treatment and hospitalization. My research program aims to improve and standardize the care of febrile young infants, aligned with parental preferences and in view of family-centred outcomes. The overarching goals of this program are first to determine how to safely reduce invasive testing and hospitalization for febrile young infants using currently available and newer diagnostic tools, and second, to better understand parental preferences and identify barriers and facilitators for shared decision-making.
Prevalence of Serious Bacterial Infections Among Febrile Infants 90 Days or Younger in a Canadian Urban Pediatric Emergency Department During the COVID-19 Pandemic. Burstein B, Anderson G, Yannopoulos A. JAMA Netw Open. 2021 Jul 1;4(7):e2116919. doi: 10.1001/jamanetworkopen.2021.16919.
Prevalence of Bacterial Meningitis Among Febrile Infants Aged 29-60 Days With Positive Urinalysis Results: A Systematic Review and Meta-analysis. Burstein B, Sabhaney V, Bone JN, Doan Q, Mansouri FF, Meckler GD. JAMA Netw Open. 2021 May 3;4(5):e214544. doi: 10.1001/jamanetworkopen.2021.4544.
Trends in Management of Children With Acute Gastroenteritis in US Emergency Departments. Burstein B, Rogers S, Klassen TP, Freedman SB. JAMA Netw Open. 2022 May 10;5(5)e2211201. doi: 10.1001/jamanetworkopen.2022.11201.
Suicidal Attempts and Ideation Among Children and Adolescents in US Emergency Departments, 2007-2015. Burstein B, Agostino H, Greenfield B. JAMA Pediatr. 2019 Jun 1;173(6):598-600. doi: 10.1001/jamapediatrics.2019.0464.
Use of Radiography in Patients Diagnosed as Having Acute Bronchiolitis in US Emergency Departments, 2007-2015. Burstein B, Plint AC, Papenburg J. JAMA. 2018 Oct 16;320(15):1598-1600. doi: 10.1001/jama.2018.9245.