Lupus • morbidity • cardiovascular disease • vasculitis • adherence to treatment • prognostic factors
My research focuses on defining and limiting the burden of cardiovascular disease and non-vascular cardiac diseases in SLE. Aside from conducting research to delineate the extent to which SLE patients suffer from sequelae of the disease (both related to cardiac and other morbidities), I have actively pursued strategies aimed at preventing cardiac disease in the systemic lupus patients that are served by the Montreal General Hospital Lupus Clinic. This has included focusing more attention on potentially reversible risk factors for cardiac disease, such as hypertension, cholesterol, antiphospholipid antibodies, and homocysteine. To the practice of annual assessments of SLE patients for general health issues, I have advocated for and successfully introduced the yearly systematic evaluation of some of these particular cardiac risk factors.
Vinet E, Labreque J, Pineau CA, Clarke AE, St-Pierre Y, Platt R, Bernatsky S A POPULATION-BASED ASSESSMENT OF LIVE BIRTHS IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS Ann Rheum Dis. 2012 Apr;71(4):557-9.
Karp I, Abrahamowicz M, Fortin PR, Pilote L, Neville C, Pineau CA, Esdaile JM LONGITUDINAL EVOLUTION OF CORONARY HEART DISEASE RISK IN SYSTEMIC LUPUS ERYTHEMATOSUS The Journal of Rheumatology, 2012 May;39(5):968-73.
Borowoy AM, Pope JE, Silverman E, Fortin PR, Pineau C, Smith CD, Arbillaga H, Gladman D, Urowitz M, Zummer M, Hudson M, Tucker L, Peschken C. NEUROPSYCHIATRIC LUPUS: THE PREVALENCE AND AUTOANTIBODY ASSOCIATIONS DEPEND ON THE DEFINITION: RESULTS FROM THE 1000 FACES OF LUPUS COHORT. Semin Arthritis Rheum. 2012 Oct;42(2):179-85.
Vinet E, Kuriya B, Pineau CA, Clarke AE, Bernatsky S, INDUCED ABORTIONS IN WOMEN WITH RHEUMATOID ARTHRITIS ON METHOTREXATE Arthritis Care Res (Hoboken). 2013 Aug;65(8):1365-9.
Bourré-Tessier J, Peschken CA, Bernatsky S, Joseph L, Clarke AE, Fortin PR, Hitchon C, Mitoo S, Smith CD, Zummer M, Pope J, Tucker L, Hudson M, Arbillaga H, Esdaile J, Carette S, Silverman E, Chédeville G, Huber AM, Belisle P, CaNIOS 1000 Canadian Faces of Lupus investigators and Pineau CA ASSOCIATION OF SMOKING WITH CUTANEOUS MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS Arthritis Care Res (Hoboken). 2013 Aug;65(8):1275-80