null Gustavo Duque, MD, PhD

Senior Scientist, RI-MUHC

Metabolic Disorders and Complications Program

Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University



osteoporosis • sarcopenia • osteosarcopenia • aging • geriatrics • gerontology • geroscience • bone • muscle • fat

Research Focus

My research focuses on the interactions between bone, muscle and fat and the elucidation of common mechanisms and pathways associated with the pathophysiology of osteoporosis, sarcopenia, osteosarcopenia and frailty in older persons. I am also looking at the effect of vitamin D, exercise and nutrition on bone and muscle mass while also working on the development of novel diagnostic and therapeutic approaches to age-related musculoskeletal diseases.

Selected Publications

Click on Pubmed to see my current publications list

  • Montero-Odasso M, van der Velde N, Martin FC, Petrovic M, Tan MP, Ryg J, Aguilar-Navarro S, Alexander NB, Becker C, Blain H, Bourke R, Cameron ID, Camicioli R, Clemson L, Close J, Delbaere K, Duan L, Duque G, Dyer SM, Freiberger E, Ganz DA, Gómez F, Hausdorff JM, Hogan DB, Hunter SMW, Jauregui JR, Kamkar N, Kenny RA, Lamb SE, Latham NK, Lipsitz LA, Liu-Ambrose T, Logan P, Lord SR, Mallet L, Marsh D, Milisen K, Moctezuma-Gallegos R, Morris ME, Nieuwboer A, Perracini MR, Pieruccini-Faria F, Pighills A, Said C, Sejdic E, Sherrington C, Skelton DA, Dsouza S, Speechley M, Stark S, Todd C, Troen BR, van der Cammen T, Verghese J, Vlaeyen E, Watt JA, Masud T; Task Force on Global Guidelines for Falls in Older Adults. World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing. 2022 Sep 2;51(9):afac205. doi: 10.1093/ageing/afac205.

  • Kirk B, Kuo CL, Xiang M, Duque G. Associations between leukocyte telomere length and osteosarcopenia in 20,400 adults aged 60 years and over: Data from the UK Biobank. Bone. 2022 Aug;161:116425. doi: 10.1016/j.bone.2022.116425.

  • Al Saedi A, Wang Z, Shah A, Brotto M, Duque G. Comparative analysis of fat composition in marrow, serum, and muscle from aging C57BL6 mice. Mech Ageing Dev. 2022 Sep;206:111690. doi: 10.1016/j.mad.2022.111690.

  • Kirk B, Lieu N, Vogrin S, Sales M, Pasco JA, Duque G. Serum levels of C-terminal telopeptide (CTX) are associated with muscle function in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2022 Jan 9:glac008. doi: 10.1093/gerona/glac008.

  • Imani M, Bani Hassan E, Vogrin S, Ch'Ng ASTN, Lane NE, Cauley JA, Duque G. Validation of a Semiautomatic Image Analysis Software for the Quantification of Musculoskeletal Tissues. Calcif Tissue Int. 2022 Mar;110(3):294-302. doi: 10.1007/s00223-021-00914-4.