null John Kildea, M.Sc., PhD
patient portals • patient empowerment • patient-centred software development • health informatics • data donation • artificial intelligence • natural language processing • neutron dosimetry • radiation-induced carcinogenesis • single-cell sequencing
My research has three axes. The first two are in health informatics, focusing on the development of patient-centred data-sharing software (Opal) and exploitation of radiotherapy data (natural language processing, dose accumulation and radiomics). At the RI-MUHC I lead the Opal Health Informatics Group, the research team that designed, developed, clinically implemented and actively supports the Opal patient portal at the MUHC. The third axis is in biophysics and aims to use single-cell DNA sequencing to improve our understanding of the mechanism(s) underlying radiation-induced carcinogenesis.
All three axes are underpinned by strong connections I have established with clinicians, patients, other researchers, industry partners and nuclear regulators. All are well funded and productive. They involve students, software developers and multidisciplinary collaborations.
Opal patient portal
Kildea J, Battista J, Cabral B, Hendren L, Herrera D, Hijal T, Joseph A. Design and Development of a Person-Centered Patient Portal Using Participatory Stakeholder Co-Design. J Med Internet Res 2019;21(2):e11371. URL: https://www.jmir.org/2019/2/e11371 DOI: 10.2196/11371.
Chu D, Schuster T, Lessard D, Mate K, Engler K, Ma Y, Abulkhir A, Arora A, Long S, de Pokomandy A, Lacombe K, Rougier H, Cox J, Kronfli N, Hijal T, Kildea J, Routy J-P, Asselah J, Lebouché B. Acceptability of a Patient Portal (Opal) in HIV Clinical Care: A Feasibility Study. Journal of Personalized Medicine. 2021; 11(2):134. https://doi.org/10.3390/jpm11020134.
Mohsen, K., Kildea, J., Lambert, S.D. et al. Exploring Cancer Patients’ Perceptions of Accessing and Experience with Using the Educational Material in the Opal Patient Portal. Support Care Cancer (2021). https://doi.org/10.1007/s00520-020-05900-4.
H. M. Patrick, L. Souhami & J. Kildea (2021) Reduction of inter-observer contouring variability in daily clinical practice through a retrospective, evidence-based intervention, Acta Oncologica, 60:2, 229-236, DOI: 10.1080/0284186X.2020.1825801.
Mathew F, Chilian C, Montgomery L, Kildea J. Development of a passive gold-foil Nested Neutron Spectrometer to validate the active current-mode He-3 measurements in a high neutron fluence rate radiotherapy environment. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Volume 985, 2021, 164662, ISSN 0168-9002, https://doi.org/10.1016/j.nima.2020.164662.