Breadcrumb

null Marcel Behr, MD, M.Sc.

Senior Scientist, RI-MUHC , Glen site

Infectious Diseases and Immunity in Global Health Program

Centre for Translational Biology

Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

Department of Medicine, Division of Infectious Diseases, MUHC

 

Keywords


tuberculosis • molecular epidemiology • bacille Calmette-Guérin (BCG) vaccine • innate immunity • Crohn's disease

Research Focus


My research focuses on mycobacteria, which are the cause of tuberculosis (TB) and TB-like diseases. Our lab uses genomic methods to study the epidemiology of TB (its spread between people) and the pathogenesis of TB (how it causes infection, and how infection progresses to disease).

Selected Publications


Click on Pubmed to see my current publications list

  • Pai M, Behr MA, Dowdy D, Dheda K, Divangahi M, Boehme C, Ginsberg A, Swaminathan S, Spigelman M, Getahun H, Menzies D, Raviglione M. Tuberculosis. Nature Reviews Disease Primers 2016 Oct 27;2:16076.: doi:10.1038/nrdp.2016.76. PMID: 27784885.

  • Behr MA, Edelstein P, Ramakrishnan L. Revisiting timetable of tuberculosis. BMJ. 2018 Aug 23;362:k2738. doi: 10.1136/bmj.k2738. PMID: 30139910.

  • Duffy SC, Srinivasan S, Schilling MA, Stuber T, Danchuk SN, Michael JS, Venkatesan M, Bansal N, Maan S, Jindal N, Chaudhary D, Dandapat P, Katani R, Chothe S, Veerasami M, Robbe-Austerman S, Juleff N, Kapur V, Behr MA. Reconsidering Mycobacterium bovis as a proxy for zoonotic tuberculosis: a molecular epidemiological surveillance study. Lancet Microbe. 2020 Jun;1(2):e66-e73. doi: 10.1016/S2666-5247(20)30038-0. PMID: 32642742.

  • Ghanem M, Dube J-Y, Wang J, McIntosh F, Houle D, Domenech P, Reed MB, Raman S, Buter J, Minnaard AJ, Moody DB, Behr MA. Heterologous production of 1-tuberculosinyladenosine in Mycobacterium kansasii models pathoevolution towards the transcellular lifestyle of Mycobacterium tuberculosis. mBio. 2020 Oct 20;11(5):e02645-20. doi: 10.1128/mBio.02645-20. PMID: 33082253.

  • Sullivan J, Lupien A, Kalthoff E, Hamela C, Taylor L, Munro K, Schmeing M, Kremer L, Behr AM. Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. PLoS Pathog. 2021 Oct 12;17(10):e1009965. doi:10.1371/journal.ppat.1009965. PMID: 34637487.