Keywords

tuberculosis • molecular epidemiology • bacille Calmette-Guérin (BCG) vaccine • innate immunity • Crohn's disease

Research Focus

My research focuses on mycobacteria, which are the cause of tuberculosis (TB) and TB-like diseases. Our lab uses genomic methods to study the epidemiology of TB (its spread between people) and the pathogenesis of TB (how it causes infection, and how infection progresses to disease).

Selected Publications

Click on to see my current publications list

• Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MVS, Schlesinger LS, Divangahi M, Reed MB, Behr MA.  N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis.  J Infect Dis. 2014 Apr;209(7):1045-54.

• Marcel A. Behr, W. Ray Waters.  Is tuberculosis a lymphatic disease with a pulmonary portal?  Lancet Infect Dis. 2014 Mar;14(3):250-5. doi: 10.1016/S1473-3099(13)70253-6. Epub 2013 Nov 22.

• Lee RS, Radomski N, Proulx J-F, Levade I, Shapiro BJ, McIntosh F, Soualhine H, Menzies D, Behr MA. Population genomics of Mycobacterium tuberculosis in the Inuit. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13609-14. doi: 10.1073/pnas.1507071112.

• Wang J, McIntosh F, Radomski N, Dewar K, Simeone R, Enninga J, Brosch R, Rocha EP, Veyrier FJ, Behr MA. Insights on the Emergence of Mycobacterium tuberculosis from the Analysis of Mycobacterium kansasii. Genome Biol Evol. 2015 Feb 25;7(3):856-70. doi: 10.1093/gbe/evv035.

• Pai M, Behr MA, Dowdy D, Dheda K, Divangahi M, Boehme C, Ginsberg A, Swaminathan S, Spigelman M, Getahun H, Menzies D, Raviglione M. Tuberculosis. Nature Reviews Disease Primers 2016 Oct 27;2:16076.: doi:10.1038/nrdp.2016.76.