null Marie-Josée Brouillette, MD
HIV • post-COVID
My research focuses on the psychosocial aspects of two medical conditions, HIV infection and the post-COVID syndrome. These studies are concerned with regulation of cognition and mood and understanding of their impact on everyday function and quality of life.
The HIV study involves characterizing 900 HIV+ individuals across Canada, followed since 2013 to elucidate factors that contribute to the development of cognitive decline and mood changes, with interventional trials being conducted in selected subgroups of individuals. This study involves interdisciplinary collaborations (neurology, neuropsychology, epidemiology, HIV clinicians and community groups) and aims to develop innovative solutions that can be applied in the clinic.
The study in post-COVID syndrome aims to characterize the profiles of symptoms experienced by people with “long COVID,” documenting the evolution of these symptoms over time and their impact on function. As part of the study, we offer self-management resources to address some of the problematic symptoms.
Brouillette MJ, Koski L, Scott S, Austin-Keiller A, Fellows LK, Mayo NE. Factors Influencing Psychological Distress During the COVID-19 Pandemic in People Aging with HIV. AIDS Research and Human Retroviruses. Published Online:10 Dec 2021. https://doi.org/10.1089/aid.2021.0024.
Koski L, Brouillette M-J, Mayo NE, Scott SC, Fellows LK, Sookman D. A Short-term Psychological Intervention for People Living with HIV During the First Wave of COVID-19. International Journal of Cognitive Therapy. Published on-line 12 November 2021. https://doi.org/10.1007/s41811-021-00127-5.
Brouillette MJ, Koski L, Forcellino L, Gasparri J, Brew BJ, Fellows LK, Mayo NE, Cysique LA. Predicting occupational outcomes from neuropsychological test performance in older people with HIV. AIDS. 2021 Sep 1;35(11):1765-1774. doi: 10.1097/QAD.0000000000002927. PMID: 33927088.
Mayo NE, Brouillette MJ, Nadeau L, Dendukuri N, Harris M, Smaill F, Smith G, Thomas R, Fellows LK; Investigators from the Positive Brain Health Now Study. A longitudinal view of successful aging with HIV: role of resilience and environmental factors. Qual Life Res. 2021 Aug 30. doi: 10.1007/s11136-021-02970-7. Epub ahead of print. PMID: 34460077.
Brouillette MJ, Fellows LK, Finch L, Thomas R, Mayo NE. Properties of a brief assessment tool for longitudinal measurement of cognition in people living with HIV. PLoS ONE 2019, 14 (3): e0213908. https://doi.org/10.1371/journal. pone.0213908.