null Michael Shevell, MD, CM, FRCP, FCAHS
cerebral palsy • developmental delay • cognitive disability • etiology • outcomes • ethics
My research focuses on the causes, consequences and outcome of children at risk for, or with, a neurodevelopmental delay, in particular cerebral palsy or global developmental delay/intellectual disability. I focus on research questions that have a pragmatic and almost immediate relevance to clinical practice affecting these populations. I am particularly interested in identifying clinical phenotypes and factors that have the potential for interventions, especially in vulnerable sub-populations of children at risk for adverse outcome, however defined. In doing so, I evaluate the diagnostic effectiveness of novel technologies enabling evidence-based refinement of our evaluation protocols, as well ethical imperatives in assessment, prediction, and intervention.
Levy JP, Ng P, Andersen J, Buckley D, Fehlings D, Kirton A, Kollas L, Pigeon N, Van Rensburg E, Wood E, Oskoui M, Shevell M. Ataxic-Hypotonic Cerebral Palsy in a Cerebral Palsy Registry: insights into a distinct subtype. Neurology: Clinical Practice 10;131-139, 2020. PMID: 32309031.
Chen A, Holzinger Dyck S, Andersen J, Buckley D, Fehlings D, Kirton A, Koclas L, Pigeon N, Van Rensburg E, Wood E, Oskoui M, Shevell M. Losing a diagnosis of Cerebral Palsy: comparing characteristics at age 2 between children with and without CP at age 5. Dev Med Child Neurology 62:83-88, 2020 Affiliations expand. PMID: 31273776.
Shevell M, Oskoui M, Wood E, Kirton A, Rensburg EV, Buckely D, Ng P, Majnemer A. Family-Centered Health Care for Children with Cerebral Palsy. Dev Med Child Neurol 61; 62-68, 2019. PMID: 30294783.
Al Amrani F, Marcovitz J, Sanon P-N, Khairy M, Saint-Martin C, Shevell M, Wintermark P. Prediction of outcome in asphyxiated newborns treated with hypothermia: Is a MRI scoring system described before the cooling era still useful? Eur J Ped Neur 22; 387-395, 2018. PMID: 29439909.
Oskoui M, Gazzellone MJ, Thiruvahindrapuram B, Zarrei M, Andersen J, Wei J, Wang Z, Wintle RF, Marshall CR, Cohn RD, Weksberg R, Stavropolous DJ, Fehlings D, Shevell MI, Scherer S. Clinically Relevant Copy Number Variants Detected in Cerebral Palsy. Nature Comm. 6: 7949. 2015. PMID: 26236009.