null Nicole Li-Jessen, PhD
upper airway health and diseases • computational medicine • tissue engingeering • point-of-care diagnostics • wearable devices
My research focuses on advancing personalized medicine in voice and upper airway dysfunctions through the development of biological computing, point-of-care diagnostics, regenerative biomaterials and Internet of Medical Things (IoMT). My team is developing non-invasive assessment of airway reflux, designing 3D printable biomaterial for laryngeal tissue and muscle reconstruction and creating wearable e-health devices for voice and upper airway monitoring. My work is funded by a Canada Research Chair, the CIHR, NSERC, SSHRC and FRQS, and by NIH in the United States.
Click on to see my current publications list
Coburn, P. T., Li, X., Li, J. Y., Kishimoto, Y., & Li‐Jessen, N. Y. K. (2022). Progress in vocal fold regenerative biomaterials: an immunological perspective. Advanced NanoBiomed Research. 2(2), 2100119.
Ridgway C., Bouhabel S., Martignetti L., Kishimoto Y., & Li-Jessen N. Y. K. (2021). Pediatric vocal fold paresis and paralysis: a narrative review. JAMA Otolaryngology – Head & Neck Surgery,147(8), 745-752. PMID: 34110365.
Coburn P. T., Herbay A. C., Berrini M., & Li-Jessen N. Y. K. (2021). An in vitro assessment of the response of THP-1 macrophages to varying stiffness of a glycol-chitosan hydrogel for vocal fold tissue engineering applications. J Biomed Mater Res A, 109(8),1337-1352. PMID: 33112473.
Fu, H., Song, P. F., Wu, Q. Y., Zhao, C., Pan, P., Li, X., Li-Jessen, N. Y. K. & Liu, X. (2019). A paper-based microfluidic platform with shape-memory-polymer-actuated fluid valves for automated multi-step immunoassays. Microsystems & Nanoengineering, 5, 50. PMID: 31636936.
Seekhao, N., Shung, C., JaJa, J., Mongeau, L., & Li-Jessen, N. Y. K. (2018). High-performance agent-based modeling applied to vocal fold inflammation and repair. Frontiers in Physiology. 9(304). PMID: 29706894.