null Nicole Li-Jessen, PhD
upper airway health and diseases • computational medicine • tissue engingeering • point-of-care diagnostics • wearable devices
My research focuses on advancing personalized medicine in voice and upper airway dysfunctions through the development of biological computing, point-of-care diagnostics, regenerative biomaterials and Internet of Medical Things (IoMT). My team is developing non-invasive assessment of airway reflux, designing 3D printable biomaterial for laryngeal tissue and muscle reconstruction and creating wearable e-health devices for voice and upper airway monitoring. My work is funded by a Canada Research Chair, the CIHR, NSERC, SSHRC and FRQS, and by NIH in the United States.
Coburn, P. T., Li, X., Li, J. Y., Kishimoto, Y., & Li‐Jessen, N. Y. K. (2022). Progress in vocal fold regenerative biomaterials: an immunological perspective. Advanced NanoBiomed Research. 2(2), 2100119.
Ridgway C., Bouhabel S., Martignetti L., Kishimoto Y., & Li-Jessen N. Y. K. (2021). Pediatric vocal fold paresis and paralysis: a narrative review. JAMA Otolaryngology – Head & Neck Surgery,147(8), 745-752. PMID: 34110365.
Coburn P. T., Herbay A. C., Berrini M., & Li-Jessen N. Y. K. (2021). An in vitro assessment of the response of THP-1 macrophages to varying stiffness of a glycol-chitosan hydrogel for vocal fold tissue engineering applications. J Biomed Mater Res A, 109(8),1337-1352. PMID: 33112473.
Fu, H., Song, P. F., Wu, Q. Y., Zhao, C., Pan, P., Li, X., Li-Jessen, N. Y. K. & Liu, X. (2019). A paper-based microfluidic platform with shape-memory-polymer-actuated fluid valves for automated multi-step immunoassays. Microsystems & Nanoengineering, 5, 50. PMID: 31636936.
Seekhao, N., Shung, C., JaJa, J., Mongeau, L., & Li-Jessen, N. Y. K. (2018). High-performance agent-based modeling applied to vocal fold inflammation and repair. Frontiers in Physiology. 9(304). PMID: 29706894.