null Roupen Hatzakorzian, MD, M.Sc.

Associate Investigator, RI-MUHC, Glen site

Metabolic Disorders and Complications Program

Assistant Professor, Department of Anesthesia, Faculty of Medicine and Health Sciences, McGill University

Department of Anaesthesia, Division of Adult Anaesthesia, MUHC



critical illness • cardiac surgery • metabolism • perioperative outcomes

Research Focus

My research focuses on improving outcomes in cardiac surgical and critically ill patients by nutritional and metabolic therapies. I am also interested in looking at the relationship of echocardiographic indices and hemodynamic outcomes in cardiac surgical and critically ill populations.

Selected Publications

Click on Pubmed to see my current publications list

  • Glucose and insulin administration while maintaining normoglycemia inhibits whole body protein breakdown and synthesis after cardiac surgery. Hatzakorzian R, Shum-Tim D, Wykes L, Hülshoff A, Bui H, Nitschmann E, Lattermann R, Schricker T. J Appl Physiol (1985). 2014 Dec 1;117(11):1380-7. PMID: 25257875.

  • Interchangeability of transthoracic and transesophageal echocardiographic right heart measurements in the perioperative setting and correlation with hemodynamic parameters. Assanangkornchai N, Villeneuve V, McDonald S, Magder S, Shum Tim D, Buithieu J, Hatzakorzian R.Int J Cardiovasc Imaging. 2023 Mar;39(3):555-563. PMID: 36399180.

  • Hyperinsulinemic-normoglycemic clamp administered together with amino acids induces anabolism after cardiac surgery. Codère-Maruyama T, Schricker T, Shum-Tim D, Wykes L, Nitschmann E, Guichon C, Kristof AS, Hatzakorzian R. Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1085-R1092. PMID: 27707724.

  • HbA1c: a prognostic biomarker in the surgical and critically ill patient population. Letourneau J, Bui H, Schricker T, Hatzakorzian R. J Cardiothorac Vasc Anesth. 2013 Aug;27(4):760-4. PMID: 22939970.

  • Parenteral amino acid supplementation with high-dose insulin prevents hypoaminoacidemia during cardiac surgery. Hong M, Wykes L, Shum-Tim D, Nitschmann E, Bui H, Nakazawa K, Codere-Maruyama T, Schricker T, Hatzakorzian R. Nutrition. 2020 Jan;69:110566. PMID: 31539818.