null Sapha Barkati, MD, MSc
tropical medicine • travel medicine • migrant health • parasitology • neglected tropical diseases • epidemiology
My research focuses on measuring the burden and improving the care of parasitic diseases such as strongyloidiasis and tegumentary leishmaniasis in vulnerable populations, with a focus on migrants and immunocompromised individuals. I am currently conducting studies on Strongyloides knowledge and awareness among Canadian physicians to build educational tools that will improve Strongyloides screening in the high-risk population. I am also studying the prevalence of Strongyloides in the immunocompromised population in non-endemic countries and the best screening strategy in that population. In collaboration with Universidad Peruana Cayetano Heredia in Lima, Peru, I am studying the response to Strongyloides stercoralis treatment in the HTLV-1 population. I am also interested in the management of tegumentary leishmaniasis in travellers and migrants. One of the ultimate goals of my research is to increase knowledge and awareness of neglected tropical diseases such as strongyloidiasis and tegumentary leishmaniasis among physicians in non-endemic countries. Another is to determine the most cost-effective strategies for Strongyloides screening in the high-risk population and the best treatment in the immunocompromised population and HTLV-1 co-infected, to inform evidence-based preventive clinical care and management guidelines.
Barkati S, Ndao M, Libman M. Cutaneous leishmaniasis in the 21st century: from the laboratory to the bedside. Curr Opin Infect Dis. 2019 Oct;32(5):419-425. doi: 10.1097/QCO.0000000000000579.
Barkati S, Gottstein B, Mu Ller N, Sheitoyan-Pesant C, Metrakos P, Chen T, Garceau R, Libman MD, Ndao M, Yansouni CP. First Human Case of Metacestode Infection Caused by Versteria sp. in a Kidney Transplant Recipient. Clin Infect Dis. 2019 Feb 1;68(4):680-683. doi: 10.1093/cid/ciy602. PMID: 30212859.
Kong LY, Vincelette J, Laplante G, Duchesne JA, Libman M, Barkati S. Intradermal pre-exposure rabies vaccination in a Canadian travel clinic: 6-year retrospective observational study. CMAJ Open. 2018 Apr 5;6(2):E168-E175. doi: 10.9778/cmajo.20170147.
Barkati S, Greenaway C, Libman MD. Strongyloidiasis in immunocompromised migrants to non-endemic countries in the era of COVID-19: What is the role for presumptive ivermectin?J Travel Med. 2021 Sep 28:taab155. doi: 10.1093/jtm/taab155. Online ahead of print.
Naeem F, Nathan K, Chivinski J, Ekmekjian T, Libman M, Barkati S. Intravenous liposomal amphotericin B efficacy and safety for cutaneous and mucosal leishmaniasis: a systematic review and meta-analysis protocol. BMJ Open. 2021 Jun 16;11(6):e045707. doi: 10.1136/bmjopen-2020-045707.