null Sergio Burgos, PhD
nutrition • metabolism • insulin resistance • skeletal muscle
My research focuses on understanding how diet influences insulin sensitivity in humans. Insulin promotes glucose storage in adipose, muscle and liver. A reduced sensitivity of target tissues to the anabolic effect of insulin is a harbinger of type 2 diabetes. Diet is the most important modifiable factor that influences diabetes risk. My laboratory conducts metabolic studies in cultured cells and in humans to characterize the effect of dietary components on skeletal muscle insulin sensitivity. The goal of my research is to develop dietary strategies that reduce people’s risk of developing type 2 diabetes.
Edick AM, Auclair O, Burgos SA. 2020. Role of Grb10 in mTORC1-dependent regulation of insulin signaling and action in human skeletal muscle cells. American Journal of Physiology Endocrinology and Metabolism. 318:E173-83.
Auclair O, Han Y, Burgos SA. 2019. Consumption of Milk and Alternatives and their contribution to nutrient intakes among Canadian adults: Evidence from the 2015 Canadian Community Health Survey-Nutrition. Nutrients.
Burgos SA, LaForce S, Zhao X. 2019. The role of dairy fat on cardiometabolic health: What is the current state of knowledge? Canadian Journal of Animal Science. 99:429-441.
Burgos SA, Chandurkar V, Tsoukas MA, Chevalier S, Morais JA, Lamarche M, Marliss EB. 2016. Insulin resistance of protein anabolism accompanies that of glucose metabolism in lean, glucose-tolerant offspring of persons with type 2 diabetes. BMJ Open Diabetes Research & Care. 4:e000312.