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nephrology • kidney transplantation • epidemiology • adherence
My research focuses on the long term outcomes of children and young adults with kidney transplants. My research focuses in particular on adolescent and young adult kidney transplant recipients, whom I have identified to be at particularly high risk of graft loss. Graft losses in this interval are often due to poor adherence to immunosuppressive medication related to developmental stage and to transfer from pediatric to adult-oriented care. I am currently leading a multi-centre study funded by the U.S. National Institutes of Health to test an intervention to improve medication adherence among 11 to 24 year-old kidney transplant recipients. I also lead a Canadian national cohort study to identify care processes and structures that promote better adherence.
Foster BJ, Dahhou M, Zhang X, Platt RW, Samuel SM, Hanley JA. Association between age and graft failure rates in young kidney transplant recipients. Transplantation. 2011 Dec 15;92(11):1237-43. doi: 10.1097/TP.0b013e31823411d7. PMID: 22124283.
Foster BJ, Dahhou M, Zhang X, Platt RW, Smith JM, Hanley JA. Impact of HLA mismatch at first kidney transplant on lifetime with graft function in young recipients. Am J Transplant. 2014 Apr;14(4):876-85. doi: 10.1111/ajt.12643. Epub 2014 Feb 19. PMID: 24612783.
Foster BJ1, Dahhou M, Zhang X, Platt RW, Hanley JA. Relative importance of HLA mismatch and donor age to graft survival in young kidney transplant recipients. Transplantation. 2013 Sep 15;96(5):469-75. doi: 10.1097/TP.0b013e318298f9db. PMID: 23759881.
Mitsnefes MM1, Laskin BL, Dahhou M, Zhang X, Foster BJ. Mortality risk among children initially treated with dialysis for end-stage kidney disease, 1990-2010. JAMA. 2013 May 8;309(18):1921-9. doi: 10.1001/jama.2013.4208. PMID: 23645144.
Foster BJ1, Platt RW, Zemel BS. Development and validation of a predictive equation for lean body mass in children and adolescents. Ann Hum Biol. 2012 May;39(3):171-82. doi: 10.3109/03014460.2012.681800. PMID: 22621754.