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null Christos Karatzios, MD, CM

Associate Investigator, RI-MUHC, Glen site

Child Health and Human Development Program

Assistant Professor, Department of Pediatrics, Faculty of Medicine and Health Sciences, McGill University

Department of Pediatrics, Division of Infectious Diseases, MUHC

 

Keywords

HIV • paediatrics • infectious diseases

Research Focus

My research focuses on paediatric HIV. Our team provides yearly robust surveillance data about this to Quebec and Canada’s public health agencies. I am the site Principle Investigator for the CIME Québec Pediatric HIV surveillance project; we report cases of paediatric HIV, and newborns of HIV-infected mothers. This data is useful at the level of the Quebec Health Ministry, and ultimately Health Canada because it informs Canadian physicians on how to manage paediatric HIV and prevent perinatal HIV infections. Our members are part of the Canadian Pediatric AIDS Research Group that establishes guidelines for prevention and treatment of HIV in children. Historically, we have also been involved in new and ultimately successful paediatric HIV medication trials. Additionally, our team has conducted efficacy vaccine trials against influenza and human papilloma viruses in HIV infected patients.

Selected Publications

Click on Pubmed to see my current publications list

  • Bitnun A, Brophy J, Samson L, Alimenti A, Kakkar F, Lamarre V, Moore D, Karatzios C, Seigel S, Sauve L, Vaudry W, Yudin MH, and Money D, for the Canadian Paediatric and Perinatal AIDS Research Group and the Infectious Diseases Committee of the Society of Obstetricians and Gynaecologists of Canada. Prevention of vertical HIV transmission and management of the HIV-exposed infant in Canada in 2014. Can J Infect Dis Med Microbiol. 2014 Mar-Apr; 25(2): 75-77. PMID: 24855474.

  • Tudor-Williams G, Cahn P, Chokephaibulkit K, Fourie J, Karatzios C, Dincq S, Opsomer M, Kakuda TN, Nijs S, L Tambuyzer L, and Tomaka FL, on behalf of the PIANO study group. Etravirine in treatment-experienced, HIV-1-infected children and adolescents: 48-week safety, efficacy and resistance analysis of the phase II PIANO study. HIV Med. 2014; 15: 513-24. DOI: 10.1111/hiv.12141. PMID: 24589294.

  • Money, Deborah M et al. “HIV viral suppression results in higher antibody responses in HIV-positive women vaccinated with the quadrivalent human papillomavirus vaccine.” Vaccine vol. 34,40 (2016): 4799-806. doi:10.1016/j.vaccine.2016.08.016 https://doi.org/10.1016/j.vaccine.2016.08.016. PMID: 27544584.

  • Marie-Julie Trahan, Marc Boucher, Christian Renaud, Christos Karatzios, Marie-Elaine Metras, PharmD, MSc, Silvie Valois, Doris G.Ransy PhD, Valérie Lamarre, Fatima Kakkar MD, MPH. Pregnancies Among the First Generation of Survivors of Perinatal HIV Infection. J Obstetr Gyn Canada. 2020; 42(4). 446-452. DOI: 10.1016/j.jogc.2019.09.022. PMID: 31882286.

  • Kakkar, Fatima; Lee, Terry; Hawkes, Michael T.; Brophy, Jason; Lindy, Samson; Singer, Joel; Dieumegard, Hinatea; Sauve, Laura; Alimenti, Ariane; Vaudry, Wendy; Seigel, Sandra; Tan, Ben; Karatzios, Christos; Lamarre, Valerie; Read, Stanley; Soudeyns, Hugo; Bitnun, Ari; EPIC4 Study Group. Challenges to achieving and maintaining viral suppression among children living with HIV. AIDS: 2020; 34(5 ). 687-697. doi: 10.1097/QAD.0000000000002454. PMID: 31794519.