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null Eva Kaufmann, DVM, PhD

Junior Scientist, RI-MUHC, Glen site

Translational Research in Respiratory Diseases Program

Centre for Translational Biology

Assistant Professor, Faculty of Dental Medicine and Oral Health Sciences, McGill University

 

Keywords

trained immunity • hematopoietic stem cells • allergic diseases • respiratory diseases

Research Focus

My research program explores the role of hematopoietic stem cells and trained immunity (“innate immune memory”) in allergic diseases. My work focus on respiratory allergies affecting both the upper and lower airways, including allergic rhinitis and asthma. By investigating the fundamental mechanisms of allergy development, my team and I aim to pave the way for new preventive and therapeutic strategies. My lab integrates animal models with human samples, applying advanced flow cytometry, imaging, and single-cell sequencing, alongside functional in vitro and in vivo approaches, to connect basic discovery with translational impact.

Selected Publications

Click on Pubmed to see my current publications list

  • Tran BT, Jeyanathan V, Cao R, Kaufmann E, King KY. Hematopoietic stem and progenitor cells as a reservoir for trained immunity. Elife. 2025 Sep 4;14:e106610.

  • Bhattarai S, Kaufmann E, Liang F, Zheng Y, Gusev E, Hamid Q, Ding J, Divangahi M, Petrof BJ. Characterization of SARS-CoV-2 Entry Genes in Skeletal Muscle and Impacts of In Vitro Versus In Vivo Infection. J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13705.

  • Sheedy FJ, Kaufmann E. Linking metabolic and epigenetic changes in immune tolerance. Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2419751121.

  • Li Q, Liang F, Bhattarai S, Divangahi M, Kaufmann E, Petrof BJ. Dynamic equilibrium of skeletal muscle macrophage ontogeny in the diaphragm during homeostasis, injury, and recovery. Sci Rep. 2024 Apr 21;14(1):9132.

  • Kaufmann E, Khan N, Tran KA, Ulndreaj A, Pernet E, Fontes G, Lupien A, Desmeules P, McIntosh F, Abow A, Moorlag SJCFM, Debisarun P, Mossman K, Banerjee A, Karo-Atar D, Sadeghi M, Mubareka S, Vinh DC, King IL, Robbins CS, Behr MA, Netea MG, Joubert P, Divangahi M. BCG vaccination provides protection against IAV but not SARS-CoV-2. Cell Rep. 2022 Mar 8;38(10):110502.