null Leonard Levin, MD, PhD

Investigator, RI-MUHC

Brain Repair and Integrative Neuroscience (BRaIN) Program

Montreal Neurological Institute

Professor, Department of Ophthalmology, Faculty of Medicine and Health Sciences, McGill University

Department of Surgery, Division of Adult Ophthalmology, MUHC



optic nerve disease • neuroprotection • retinal ganglion cells • axonal degeneration

Research Focus

My research focuses on understanding the mechanisms underlying axonal degeneration in retinal ganglion cells, the development of pharmacological approaches for interrupting degeneration, and the use of translational methods to find and test novel clinical therapies for optic neuropathies.

Selected Publications

Click on Pubmed to see my current publications list

  • Levin LA, Patrick C, Choudry NB, Sharif, NA, Goldberg JL. Neuroprotection in neurodegenerations of the brain and eye: Lessons from the past and directions for the future. In press.

  • Almasieh M, Faris H, Levin LA. Pivotal Roles for Membrane Phospholipids in Axonal Degeneration. Int J Biochem Cell Biol. 2022 Jul 19:106264. doi: 10.1016/j.biocel.2022.106264. Epub ahead of print. PMID: 35868612.

  • Van Gelder RN, Chiang MF, Dyer MA, Greenwell TN, Levin LA, Wong RO, Svendsen CN. Regenerative and restorative medicine for eye disease. Nat Med. 2022 Jun;28(6):1149-1156. doi: 10.1038/s41591-022-01862-8. Epub 2022 Jun 17. PMID: 35715505.

  • Cukurova F, Gustavson BP, Griborio-Guzman AG, Levin LA. A quantitative approach to the spread of variance in translational research using Monte Carlo simulation. Sci Rep. 2022 Apr 15;12(1):6274. doi: 10.1038/s41598-022-09921-3. PMID: 35428790.

  • Levin LA, Sengupta M, Balcer LJ, Kupersmith MJ, Miller NR. Report From the National Eye Institute Workshop on Neuro-Ophthalmic Disease Clinical Trial Endpoints: Optic Neuropathies. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):30. doi: 10.1167/iovs.62.14.30. PMID: 34846515.