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null Thomas Mavrakanas, MD, M.Sc.

Scientist, RI-MUHC, 5252 de Maisonneuve site

Cardiovascular Health Across the Lifespan Program

Centre for Outcomes Research and Evaluation

Associate Professor, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University

 

Keywords

chronic kidney disease • kidney failure • cardiovascular disease • anticoagulation • cardiorenal syndromes • coronary disease

Research Focus

My research focuses on the causes of and treatments for cardiovascular disease in patients with advanced chronic kidney disease (CKD), across two main axes: a) cardiorenal interactions, and b) anticoagulation and thromboembolic disease in CKD. I have significant expertise in designing pharmacokinetic or observational studies and in designing and conducting clinical trials. My work aims to optimize management of patients with CKD and cardiovascular disease in order to prevent occurrence of myocardial infarction, stroke, or admission for heart failure, as well as to slow down CKD progression to kidney failure. A list of ongoing projects can be found here.

Selected Publications

Click on Pubmed to see my current publications list

  • Mavrakanas TA, Marsot A, Tsirella E, Rios N, Gritsas A, Suri RS. Kidney Int Rep 2024; 9(10): 3049-3052. PMID: 39430196.

  • Marques P, Mavrakanas TA, Guida J, Gédéon T, Emami A, Alaamiri A, Ho D, Possik E, Zhang G, Tsoukas MA, Sharma A. Utilizing synchronous care to improve cardiovascular and renal health among patients with type 2 diabetes: Proof-of-concept results from the DECIDE-CV clinical programme. Diabetes Obes Metab 2024; 26(8): 3448-3457. PMID: 38831564.

  • Mavrakanas TA, Garlo K, Charytan DM. Apixaban versus no anticoagulation in patients undergoing long-term dialysis with incident atrial fibrillation. Clin J Am Soc Nephrol 2020; 15(8): 1146-1154. PMID: 32444398.

  • Mavrakanas TA, Samer CF, Nessim S, Frisch G, Lipman ML. Apixaban pharmacokinetics at steady state in hemodialysis patients. J Am Soc Nephrol 2017; 28(7): 2241-2248. PMID: 28302754.

  • Mavrakanas TA, Khattak A, Singh K, Charytan DM. Epidemiology and natural history of the cardiorenal syndromes in a cohort with echocardiography. Clin J Am Soc Nephrol 2017; 12(10): 1624-1633. PMID: 28801528.