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null Vincent Mooser, MD

Affiliate Investigator, RI-MUHC

Cardiovascular Health Across the Lifespan Program

Professor, Department of Human Genetics, Faculty of Medicine and Health Sciences, McGill University

 

Keywords

genomic medicine • genetics • pharmaceutical sciences

Research Focus

My research focuses on the usage of human genetics and genomics to contribute to the discovery and development of novel therapeutics and biomarkers, in a disease-agnostic manner. To that end, the team I have assembled at McGill (Canada Excellence Research Chair in Genomic Medicine) encompasses expertise in population genomics, computational genomics, functional genomics, multi-omics and drug target discovery. We are developing new analytical methods, building up new datasets and exploiting large, publicly available datasets.

Selected Publications

Click on Pubmed to see my current publications list

  • Trajanoska K, Bhérer C, Taliun D, Zhou S, Richards JB, Mooser V. “From target discovery to clinical drug development with human genetics.” Nature vol. 620,7975 (2023): 737-745. doi:10.1038/s41586-023-06388-8. PMID: 37612393.

  • Delabays B, Trajanoska K, Walonoski J, Mooser V “Cardiovascular Pharmacogenetics: From Discovery of Genetic Association to Clinical Adoption of Derived Test.” Pharmacological reviews vol. 76,5 791-827. 15 Aug. 2024, doi:10.1124/pharmrev.123.000750. PMID: 39122647.

  • Delabays B, De Paoli C, Miller-Nesbitt A, Mooser V. Delabays, Benoît et al. “Genetically Enriched Clinical Trials for Precision Development of Noncancer Therapeutics: A Scoping Review.” Annual review of pharmacology and toxicology vol. 65,1 (2025): 149-167. doi:10.1146/annurev-pharmtox-031524-021631. PMID: 39348854.

  • COVID-19 Host Genetics Initiative. “Mapping the human genetic architecture of COVID-19.” Nature vol. 600,7889 (2021): 472-477. doi:10.1038/s41586-021-03767-x PMID: 34237774.