RI-MUHC ANNUAL REPORT 2020

RESEARCH HIGHLIGHTS

Radiation therapy to treat broken hearts

MUHC cardiologists and radiation oncologists can treat patients with severe arrhythmias using precise radiotherapy, targeting abnormal parts of the heart.

Dr. Martin Bernier leads study gathering data on this innovative technique.

New targets for treatment of valve disease

Identification of new genes (FADS1/2) involved in aortic stenosis will lead to new treatments and provide options to surgery.

Jamie Engert (PhD) and Dr. George Thanassoulis lead this study (JAMA Cardiology).

Advancing heart imaging research with Canada’s most sophisticated MRI

New cardiac magnetic resonance imaging equipment allows us to develop methods that make cardiovascular diagnostic workups faster, safer and more accurate.

Dr. Matthias Friedrich leads Cardiovascular Imaging Core at the MUHC.

SELECTED PUBLICATIONS

Alexandra B. Cooke, Kaberi Dasgupta, Bart Spronck, J. E. Sharman, Stella S. Daskalopoulou. Adults with Type 2 Diabetes Mellitus Exhibit a Greater Exercise-Induced Increase in Arterial Stiffness and Vessel Hemodynamics. Hypertension 75(6):1565-1573, 2020.

Amandeep Kaur, Sharon T. Mackin, Kenny Schlosser, Fui Lin Wong, Malik Elharram, Christian Delles, Duncan J. Stewart, Natalie Dayan, Tara Landry, Louise Pilote. Systematic review of microRNA biomarkers in acute coronary syndrome and stable coronary artery disease. Cardiovascular research 116 (6) 1113-1124, 2020.

Brahim Redouane, Stephen J. Greene, Marat Fudim, Muthiah Vaduganathan, Andrew P. Ambrosy, Jie-Lena Sun, Adam D. DeVore, Steven E. McNulty, Robert J. Mentz, Adrian F. Hernandez, G.Michael Felker, Lauren B. Cooper, Barry A. Borlaug, Eric J. Velazquez, Kenneth B. Margulies, Ahbinav Sharma. Effects of Liraglutide on Worsening Renal Function Among Patients With Heart Failure With Reduced Ejection Fraction: Insights From the FIGHT Trial. Circulation Heart Failure 13(5):e006758, 2020.

Daniala L. Weir, Aude Motulsky, Michal Abrahamowicz, Todd Campbell Lee, Steven George Morgan, David Llewellyn Buckeridge, Robyn M. Tamblyn. Challenges at Care Transitions: Failure to Follow Medication Changes Made at Hospital Discharge. American Journal of Medicine 132(10):1216-1224.e5, 2019.

Emmanouil S. Brilakis, Kambis Mashayekhi, Etsuo Tsuchikane, […] Stéphane Rinfret. Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention: A Global Expert Consensus. Circulation 140(5):420-433, 2019.

Fei Wang, Lee Harel-Sterling, Sarah Cohen, Aihua Liu, James M. Brophy, Gilles Paradis, Ariane J. Marelli. Heart failure risk predictions in adult patients with congenital heart disease: A systematic review. Heart 105(21): 1661-1669, 2019.

Karol M. Pencina, George Thanassoulis, John T. Wilkins, Vasan S. Ramachandran, Ann Marie Navar, Eric David Peterson, Michael J. Pencina, Allan David Sniderman. Trajectories of Non–HDL Cholesterol Across Midlife: Implications for Cardiovascular Prevention. Journal of the American College of Cardiology 74(1):70-79, 2019.

Mahyar Etminan, Mohit Sodhi, Saeed Ganjizadeh-Zavareh, Bruce C. Carleton, Abbas Kezouh, James M. Brophy. Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation. Journal of the American College of Cardiology 74(11):1444-1450, 2019.

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