RI-MUHC Annual Report

RI-MUHC ANNUAL REPORT 2022

YEAR IN REVIEW

INJURY REPAIR RECOVERY (IRR) PROGRAM

RESEARCH HIGHLIGHTS

The Clinical Innovation Platform opens at the RI-MUHC

The Clinical Innovation Platform (CLIP) launched in September 2021, thanks to a donation from National Bank of Canada and the strong support of the Montreal General Hospital Foundation and RI-MUHC. The mission of the CLIP is to support innovative solutions to unmet clinical needs and challenges and accelerate the adoption of technologies into the market and healthcare system. Spanning a wing on the ninth floor of the Montreal General Hospital (MGH), the CLIP has close ties to researchers in the Injury Repair Recovery Program.

Dr. Gerald Fried describes remarkable accomplishments since the CLIP launched in the central feature of this report, and the MGH Foundation highlights the heroic support behind this initiative in the section, “Your support.”

Left to right: Dr. Jake Barralet, Jean-Guy Gourdeau, Judith Ménard, Dr. Gerald Fried, Dr. Rhian Touyz and Dr. Pierre Gfeller celebrate the launch of the Clinical Innovation Platform (CLIP); winners of the 2021-2022 McGill Clinical Innovation Competition visit the CLIP

Surgical Robotics Centre: A vision for excellence

Housed in the new Clinical Innovation Platform at the RI-MUHC, the Surgical Robotics Centre aims to become one of North America’s centres of excellence in the field of surgical robotics. Its focus is on developing next-generation surgical robots for unmet clinical needs. With guidance from Amir Hooshiar, PhD, a postdoctoral fellow in the Injury Repair Recovery Program at the RI-MUHC, the centre formed two funded industrial collaborations with the robotics company Kinova in its first year.

Learn more about the Clinical Innovation Platform and Surgical Robotics Centre.

Graduate students and trainees conducting research at the Surgical Robotics Centre within the Clinical Innovation Platform

Selected IRR Program news links

SELECTED PUBLICATIONS

Julio F Fiore Jr, Charbel El-Kefraoui, Marc-Aurele Chay, Philip Nguyen-Powanda, Uyen Do, Ghadeer Olleik, Fateme Rajabiyazdi, Araz Kouyoumdjian, Alexa Derksen, Tara Landry, Alexandre Amar-Zifkin, Amy Bergeron, Agnihotram V Ramanakumar, Marc Martel, Lawrence Lee, Gabriele Baldini, Liane S Feldman. Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials: Lancet, 2022. doi: 10.1016/S0140-6736(22)00582-7.

Joseph Jao Yiu Sung, Loren A. Laine, Ernst J. Kuipers, Alan N.G. Barkun. Towards personalised management for non-variceal upper gastrointestinal bleeding: Gut, 70(5): 818-824, 2021. doi: 10.1136/gutjnl-2020-323846.

Benjamin Dalisson, Baptiste Charbonnier, Ahmed Adel Aoude, Mirko S. Gilardino, E. J. Harvey, Nicholas M. Makhoul, Jake Barralet. Skeletal regeneration for segmental bone loss: Vascularised grafts, analogues and surrogates: Acta Biomaterialia, 136: 37-55, 2021. doi: 10.1016/j.actbio.2021.09.053.

Marc Olivier Martel, Alice Bruneau, Robert R. Edwards. Mind-body approaches targeting the psychological aspects of opioid use problems in patients with chronic pain: evidence and opportunities: Translational Research 234: 114-128, 2021. doi: 10.1016/j.trsl.2021.02.013.

Chelsia Gillis, Olle H. Ljungqvist, Franco M. Carli. Prehabilitation, enhanced recovery after surgery, or both? A narrative review: British Journal of Anaesthesia 128(3): 434-448, 2022. doi: 10.1016/j.bja.2021.12.007.

Emily Newell, Mark Driscoll. Investigation of physiological stress shielding within lumbar spinal tissue as a contributor to unilateral low back pain: A finite element study: Computers in Biology and Medicine 133, 2021. doi: 10.1016/j.compbiomed.2021.104351.

Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Peter F. Jarzem, Michael H. Weber, Jean Albert Ouellet, Lisbet Haglund. Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin: Arthritis Research and Therapy 23(1), 2021. doi: 10.1186%2Fs13075-021-02504-z.

Jose Luis Ramírez García Luna, Karla Rangel-Berridi, Ore Oluwa Olasubulumi, Derek Hadar Rosenzweig, Janet E. Henderson, Rahul Gawri, Paul André Martineau. Enhanced Bone Remodeling After Fracture Priming: Calcified Tissue International 110(3): 349-366, 2022. doi: 10.1007/s00223-021-00921-5.

Pierre Moffatt, Iris Boraschi-Diaz, Juliana Marulanda, Ghalib K. Bardai, Frank Rauch. Calvaria bone transcriptome in mouse models of osteogenesis imperfect: International Journal of Molecular Sciences 22(10), 2021. doi: 10.3390/ijms22105290.

Fateme Rajabiyazdi, Roshni Alam, Aditya Pal, Joel Montanez, Susan Law, Nicolò Pecorelli, Yusuke Watanabe, Luciana Dias Chiavegato, Massimo Falconi, Satoshi Hirano, Nancy E. Mayo, Lawrence F. Lee, Liane S. Feldman, Julio F. Fiore Jr. Understanding the Meaning of Recovery to Patients Undergoing Abdominal Surgery: JAMA Surgery 156(8): 758-765, 2021. doi: 10.1001%2Fjamasurg.2021.1557.