YEAR IN REVIEW
TRANSLATIONAL RESEARCH IN RESPIRATORY DISEASES (RESP) PROGRAM
Harnessing the power of innate immunity
Stem cells are the marrow of the tuberculosis (TB) pandemic. A study led by Maziar Divangahi, PhD, found that not only can stem cells be targeted for protective vaccination, but they can also be hijacked by a pathogen to increase TB virulence.
Understanding how to harness the power of innate immunity is a promising novel avenue, not only for TB, but for other infectious diseases like COVID-19. Cell.
Sleep apnea treatment reduces heart problems in patients with prediabetes, a new study finds
Dr. Sushmita Pamidi’s team found that continuous positive airway pressure treatment at night can lower daytime resting heart rate in patients with prediabetes who have obstructive sleep apnea, reducing their risk of cardiovascular disease. J Am Heart Assoc.
Triage test for pulmonary tuberculosis
Deep learning-based radiological image analysis met WHO-recommended minimal accuracy for pulmonary tuberculosis triage tests. This could facilitate use of chest X‑rays in resource-limited settings.
RESP Program researchers Faiz Ahmad Khan, MD, MPH (first author), Andrea Benedetti, PhD, and Dick Menzies, MD, were co-authors of the study. Lancet Digit Health.
Selected news links
- Sleep apnea treatment reduces heart problems in patients with prediabetes, a new study finds
- Stem cells are the marrow of the TB pandemic, which still kills one person every 22 seconds
- Old drug, new therapy: RI-MUHC-sponsored phase III clinical trial ready to test repurposed dapsone to tone down lung inflammation caused by COVID-19: Reformulated and patented version of well-known generic drug could prove to be a quick, safe and cost-eff
- Nip it in the bud: New study will attack SARS-Cov2 where it multiplies RI-MUHC researchers initiate a clinical trial of ciclesonide to possibly prevent mild cases of COVID-19 from worsening
- Could a different testing strategy reduce healthcare workers’ isolation after unprotected exposure to a confirmed case of COVID-19?
- Saliva samples for COVID-19 testing: as good as nasopharyngeal swabs, but cheaper
- MORE RESP Program news