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neurology • epidemiology • aging • measurement • biostatistics
My research focuses on the study of neurological disorders in the population. I have conducted research on multiple sclerosis, Parkinson's disease, epilepsy, amyotrophic lateral sclerosis and dementia. I am interested in identifying the population burden of these diseases including the frequency of occurrence, and I also evaluate risk factors and factors that influence the disease course. I work to develop and to validate methods of ascertaining neurological disease in large studies in the population when it is not feasible to include a physician assessment. Recently I have become interested in the physical and mental health of aging veterans and have developed an emerging research program in this area. As co-Principal investigator on the Canadian Longitudinal Study on Aging, a 20-year study of 50,000 participants aged 45-85, I lead the Neurological Conditions Initiative and the Veterans' Health Initiative.
Keezer MR, Pelletier A, Stechysin B, Veilleux M, Jetté N, Wolfson C. The diagnostic test accuracy of a screening questionnaire and algorithm in the identification of adults with epilepsy. Epilepsia. 2014 Nov;55(11):1763-71. doi: 10.1111/epi.12805. Epub 2014 Oct 13. PMID: 25312856.
Magalhaes S, Wolfson C. Harmonization: a methodology for advancing research in multiple sclerosis. Acta Neurol Scand Suppl. 2012;(195):31-5. doi: 10.1111/ane.12031. PMID: 23278654.
Tansey CM, Raina P, Wolfson C. Veterans' physical health. Epidemiol Rev. 2013;35:66-74. doi: 10.1093/epirev/mxs005. Epub 2012 Dec 13. PMID: 23243049.
Postuma RB, Montplaisir JY, Pelletier A, Dauvilliers Y, Oertel W, Iranzo A, Ferini-Strambi L, Arnulf I, Hogl B, Manni R, Miyamoto T, Mayer G, Stiasny-Kolster K, Puligheddu M, Ju Y, Jennum P, Sonka K, Santamaria J, Fantini ML, Zucconi M, Leu-Semenescu S, Frauscher B, Terzaghi M, Miyamoto M, Unger MM, Cochen De Cock V, Wolfson C. Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study. Neurology. 2012 Jul 31;79(5):428-34. doi: 10.1212/WNL.0b013e31825dd383. Epub 2012 Jun 27. PMCID: PMC3405255.
Kirkland SA, Griffith LE, Menec V, Wister A, Payette H, Wolfson C, Raina PS. Mining a Unique Canadian Resource: The Canadian Longitudinal Study on Aging. Can J Aging. 2015 Sep;34(3):366-77. doi: 10.1017/S071498081500029X. No abstract available. PMID: 26300192.