null Christina Wolfson, B.Sc., M.Sc., PhD

Senior Scientist, RI-MUHC

Brain Repair and Integrative Neuroscience (BRaIN) Program

Centre for Outcomes Research and Evaluation

Professor, Department of Medicine and Department of Epidemiology, Biostatistics & Occupational Health, Faculty of Medicine and Health Sciences and School of Population and Global Health, McGill University



neurology • epidemiology • aging • measurement • biostatistics

Research Focus

My research focuses on the study of neurological disorders in the population. I have conducted research on multiple sclerosis, Parkinson's disease, epilepsy, amyotrophic lateral sclerosis and dementia. I am interested in identifying the population burden of these diseases including the frequency of occurrence, and I also evaluate risk factors and factors that influence the disease course. I work to develop and to validate methods of ascertaining neurological disease in large studies in the population when it is not feasible to include a physician assessment. Recently I have become interested in the physical and mental health of aging veterans and have developed an emerging research program in this area. As co-Principal investigator on the Canadian Longitudinal Study on Aging, a 20-year study of 50,000 participants aged 45-85, I lead the Neurological Conditions Initiative and the Veterans' Health Initiative.

Selected Publications

Click on Pubmed to see my current publications list

  • Nguyen QD, Moodie EM, Forget MF, Desmarais P, Keezer MR, Wolfson C. Health Heterogeneity in Older Adults: Exploration in the Canadian Longitudinal Study on Aging. J Am Geriatr Soc. 2020 Nov 5. doi: 10.1111/jgs.16919. Epub ahead of print. PMID: 33155270.

  • Wolfson C, Fereshtehnejad SM, Pasquet R, Postuma R, Keezer MR. High burden of neurological disease in the older general population: results from the Canadian Longitudinal Study on Aging. Eur J Neurol. 2019 Feb;26(2):356-362. doi: 10.1111/ene.13823. Epub 2018 Oct 31. PMID: 30300458.

  • Raina P, Wolfson C, Kirkland S, Griffith LE, Balion C, Cossette B, Dionne I, Hofer S, Hogan D, van den Heuvel ER, Liu-Ambrose T, Menec V, Mugford G, Patterson C, Payette H, Richards B, Shannon H, Sheets D, Taler V, Thompson M, Tuokko H, Wister A, Wu C, Young L. Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA). Int J Epidemiol. 2019 Dec 1;48(6):1752-1753j. doi: 10.1093/ije/dyz173. Erratum in: Int J Epidemiol. 2019 Dec 1;48(6):2066. PMID: 31633757.

  • Karunananthan S, Moodie EEM, Bergman H, Payette H, Wolfson D, Diehr PH, Wolfson C. The association between physical function and proximity to death in older adults: a multilevel analysis of 4,150 decedents from the Cardiovascular Health Study. Ann Epidemiol. 2019 Jul;35:59-65.e5. doi: 10.1016/j.annepidem.2019.04.005. Epub 2019 Apr 18. PMID: 31221508.

  • Magalhaes S, Pugliatti M, Riise T, Myhr KM, Ciampi A, Bjornevik K, Wolfson C. Shedding light on the link between early life sun exposure and risk of multiple sclerosis: results from the EnvIMS Study. Int J Epidemiol. 2019 Aug 1;48(4):1073-1082. doi: 10.1093/ije/dyy269. PMID: 30561654.