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angle-left Erwin Schurr, PhD

Senior Scientist, RI-MUHC , Glen site

Infectious Diseases and Immunity in Global Health Program

Centre for Translational Biology

Professor, Department of Medicine, Faculty of Medicine, McGill University

 

Keywords


tuberculosis • leprosy • complex traits • transcriptomics • systems biology

Research Focus


My research focuses on the identification and evaluation of host genetic factors in tuberculosis and leprosy. We are working with partner groups in endemic countries for those diseases and are applying modern concepts of genetics, genomics and sytems biology to our analyses.

Selected Publications


Click on Pubmed to see my current publications list

  • V.M. Fava, Y.Z. Xu, G. Lettre, N.V. Thuc, M. Orlova, V.H. Thai, G. Cambri, S. Tao, L. Ramanuj, L. Adams, A. Cobat, A. Alcaïs, L. Abel, E. Schurr Pleiotropic effects for Parkin and LRRK2 in leprosy reversal reactions and Parkinson’s disease Proc. Natl. Acad. Sci. USA 116:15616-15624, 2019; PMID: 31308240.

  • J. Manry, Y. Nédélec, V.M. Fava, A. Cobat, M. Orlova, G. Laval, L.B. Barreiro, E. Schurr Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation PLoS Genet., 13(8):e1006952, 2017; PMID: 28793313.

  • V.M. Fava, J. Manry, A. Cobat, M. Orlova, N.V. Thuc, M.O. Moraes, C. Sales-Marques, M.M.A. Stefani, A-C.P. Latini, A.F. Belone, V.H. Thai, L. Abel, A. Alcais, and E. Schurr A Genome Wide Association Study Identifies a lncRNA as Risk Factor for Pathological Inflammatory Responses in Leprosy PLoS Genet. 13(2):e1006637, 2017; PMID: 28222097.

  • A. Cobat, L. Abel, A. Alcaïs, E. Schurr “A General Efficient and Flexible Approach for Genome-Wide Association Analyses of Imputed Genotypes in Family-Based Designs” Genet. Epidemiol., 38:560-571, 2014; PMID: 25044438.

  • L. Abel, J. El-Baghdadi, A. Bousfiha, J.L. Casanova, E. Schurr Human genetics of tuberculosis: A long and winding road Phil.Trans. Roy. Soc. B, 369:2014; PMID: 24821915.