Asset Publisher

angle-left Laurent Legault, MD

Scientist, RI-MUHC , Glen site

Child Health and Human Development Program

Centre for Outcomes Research and Evaluation

Assistant Professor, Department of Pediatrics, Faculty of Medicine, McGill University

Department of Pediatrics, Division of Endocrinology and Metabolism, MUHC

 

Keywords


diabetes • prevention • obesity • technology

Research Focus


My research focuses on the development of an a closed loop system (also known as artifical pancreas) for the treatment of type 1 diabetes, as well as the prevention and management of pediatric obesity and its complications, including type 2 diabetes and prevention of type 1 diabetes.

Selected Publications


  • Haidar A, Legault L, Dallaire M, Alkhateeb A, Coriati A, Messier V, Cheng P, Millette M, Boulet B, Rabasa-Lhoret R. Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial. CMAJ. 2013 Mar 5;185(4):297-305. doi: 10.1503/cmaj.121265. Epub 2013 Jan 28. PMID: 23359039.

  • Haidar A, Legault L, Messier V, Mitre TM, Leroux C, Rabasa-Lhoret R. Comparison of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional insulin pump therapy for glycaemic control in patients with type 1 diabetes: an open-label randomised controlled crossover trial. Lancet Diabetes Endocrinol. 2015 Jan;3(1):17-26. doi: 10.1016/S2213-8587(14)70226-8. Epub 2014 Nov 27. PMID: 25434967.

  • Perez A, Holt N, Gokiert R, Chanoine JP, Legault L, Morrison K, Sharma A, Ball G. Why don't families initiate treatment? A qualitative multicentre study investigating parents' reasons for declining paediatric weight management. Paediatr Child Health. 2015 May;20(4):179-84. PMID: 26038633.

  • Haidar A, Legault L, Matteau-Pelletier L, Messier V, Dallaire M, Ladouceur M, Rabasa-Lhoret R. Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial. Lancet Diabetes Endocrinol. 2015 Aug;3(8):595-604. doi: 10.1016/S2213-8587(15)00141-2. Epub 2015 Jun 8. PMID: 26066705.

  • Legault L. Is the artificial pancreas coming to a home near you? Lancet Diabetes Endocrinol. 2015 Dec;3(12):916-7. doi: 10.1016/S2213-8587(15)00369-1. Epub 2015 Sep 30. PMID: 26432774.