Daniel Dufort, PhD
Embryo implantation • placenta • preterm birth • embryo-uterine crosstalk • uterine development
My research focuses on elucidating the embryo-uterine communication that is required for successful implantation of the embryo. We are using molecular, embryological, and genetic approaches to identify the signaling pathways and their roles in the implantation process. We are also interested in elucidating the role of maternal signals in proper development and function of the placenta which are often associated with complications during pregnancy such as preeclampsia and preterm birth.
Hari Krishna Thulluru, Craig Park, Daniel Dufort, Gunilla Kleiverda, Cees Oudejans, Marie van Dijk. 2013. Maternal Nodal inversely affects NODAL and STOX1 expression in the fetal placenta. Front Genet. 2013 Aug 27;4:170
Craig B Park and Daniel Dufort. 2013. Nodal Signaling Components during the Preparation, Execution and Maintenance of Embryo Implantation 2013 Jan 24;145(2):R55-64
Craig B Park, Francesco J Demayo, John P Lydon, and Daniel Dufort. 2012. Nodal in the Uterus Is Necessary for Proper Placental Development and Maintenance of Pregnancy. Biol Reprod. Jun 28;86(6):194
Craig Park and Daniel Dufort. Nodal expression in the uterus is regulated by the embryo. Biol Reprod. 2011 Jun;84(6):1103-10. Epub 2011 Jan 26.
Craig Park and Daniel Dufort. IFPA Trophoblast Research Award Lecture: The Multifaceted Role of Nodal Signaling During Mammalian Reproduction. Placenta. 2011 Mar;32 Suppl 2:S125-9. Epub 2010 Dec 31.