CHAL Researchers

The Cardiovascular Health Across the Lifespan (CHAL) Program brings together seven basic researchers, thirty clinician-scientists and eight health outcomes researchers. Researchers from the Centre for Translational Biology (CTB) conduct basic research projects related to vascular function and related diseases, especially atherosclerosis, hypercholesterolemia and vascular injury. Investigators from the Centre for Innovative Medicine (CIM) focus their research on surgery outcomes and on improving prevention and care in patients affected by such cardiac diseases as heart failure, arrhythmias and valve diseases. Investigators from the Centre for Outcomes Research and Evaluation (CORE) seek to develop networks, databases and new tools to improve population health. These include epidemiological outcome and intervention studies on congenital heart disease (CHD), and different factors (genetic, environmental, gender-based) for cardiovascular diseases. CHAL researchers are based at the Glen site, at the heritage site of the Royal Victoria Hospital of the MUHC and at 5252 de Maisonneuve Boulevard W.

Centre for Translational Biology (CTB)
Centre for Innovative Medicine (CIM)
Centre for Outcomes Research and Evaluation (CORE)

Subheading - Centre for Translational Biology (CTB)

Centre for Translational Biology (CTB)

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Renzo Cecere, MD

Heart failure

heart assist devices

mitral valve

stem cells

medical device design

Stella Daskalopoulou, MD, M.Sc., DIC, PhD

atherosclerosis

vascular biology

arterial stiffness and vessel hemodynamics

hypertension

cardiovascular risk factors

James Engert, PhD

Atherosclerosis

haplotypes

association studies

linkage disequilibrium

single-nucleotide polymorphisms (SNPs)

Jacques Genest, MD

lipoproteins

high-density lipoprotein (HDL)

familial hypercholesterolemia

genetics

ABCA1

Robert Kiss, PhD

cholesterol

intracellular trafficking

cell biology

microscopy

Adel Schwertani, PhD

Cardiology

heart

vasoactive substances

atherosclerosis

pulmonary hypertension

Subheading - Centre for Innovative Medicine (CIM)

Centre for Innovative Medicine (CIM)

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Dominic Chalut, MD

asthma

toxicology

quality assurance

trauma

pediatric emergency medicine

Robert Côté, MD

stroke

stroke prevention

acute management

clinical research

Vidal Essebag, MD, PhD

Epidemiology

statistical analysis

methodology

database analysis

data management

Matthias Friedrich, MD, FESC, FACC

Cardiovascular magnetic resonance

myocardial ischemia

coronary heart disease

acute myocardial infarction

myocarditis

Nadia Giannetti, MD

Défaillance cardiaque

greffe cardiaque

cardiomyopathie

heart transplantation

Ronald Gottesman, MD

Simulation

medical education

clinical trials

expert systems

Thao Huynh, MD

cardiovascular

sex and gender

ethnicity

knowledge translation

guidelines

Kevin Lachapelle, MD

Marrow stromal cells

angiogenesis

revascularization

Ilka Lowensteyn, PhD

Cardiac rehabilitation

exercise physiology

kinesiology

prevention

wellness

Sheldon Magder, MD

Vascular biology

endothelial function

nitric oxide

estrogen

oxygen radicals

David Mulder, MD

General thoracic surgery

lung cancer

thoracic trauma

airway injury

sports medicine

Nicolo Piazza, MD, PhD, FRCO(C), FESC

Aortic Valve

mitral Valve

transcatheter valves

transcatheter aortic valve implantation

transcatheter aortic valve replacement

Sam Shemie, MD

Brain death

neurological determination of death

organ donation

organ donor management

pediatric

Dominique Shum-Tim, MD, M.Sc.

Pediatric cardiac surgery

cardiopulmonary bypass

hypothermia

circulatory arrest

systemic inflammatory response

Susan Solymoss, MD

thrombosis

anticoagulation

treatment

prevention

hemostasis

Oren Steinmetz, MD

aneurysm

carotid stenosis

endovascular

Subheading - Centre for Outcomes Research and Evaluation (CORE)

Centre for Outcomes Research and Evaluation (CORE)

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Michal Abrahamowicz, PhD

biostatistics

cohort studies

comparative effectiveness

confounding

instrumental variables

James Brophy, MD, PhD

Cardiovascular epidemiology

medical decision making.

Natalie Dayan, MD, M.Sc., FRCPC

epidemiology

vascular

perinatal

women's health

Mark Goldberg, BSc, MSc, PhD

epidemiology

environment

occupation

cancer

cardiorespiratory diseases

Ariane Marelli, MD, MPH, FRCPC, FACC, FAHA

health services

epidemiology

congenital heart disease

cardiovascular

cardiology

Louise Pilote, MD, MPH, PhD

pharmacoepidemiology

comparative effectivenesse

sex differences in cardiovascular diseases

outcomes research

cardiovascular epidemiology

Allan Sniderman, MD

Prevention

cardiovascular

disease

atherosclerosis

apoB

Robyn Tamblyn, MScN, M.Sc., PhD, CM

Health services

medical education

medical informatics

practice changes

pharmacoepidemiology

George Thanassoulis, MD

Genetics

genomics

cardiovascular disease

aortic stenosis

myocardial infarction